Trine Nielsen

Research interests

Publications

• Microbiome and metabolome features of the cardiometabolic disease spectrum

  Nature Medicine · 2022 · 10.1038/s41591-022-01688-4

• Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

  Gut · 2022 · 10.1136/gutjnl-2021-325753

• Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

  Gut · 2022 · 10.1136/gutjnl-2021-325753

• Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

  Gut · 2021 · 10.1136/gutjnl-2020-323314

• Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

  Gut · 2021 · 10.1136/gutjnl-2020-323314

• Combinatorial, additive and dose-dependent drug–microbiome associations

  Nature · 2021 · 10.1038/s41586-021-04177-9

• Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2269-x

• Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

  Nature Communications · 2020 · 10.1038/s41467-020-19589-w

• Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

  Diabetologia · 2019 · 10.1007/s00125-019-4848-7

• Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

  Microbiome · 2018 · 10.1186/s40168-018-0472-x

• Aberrant intestinal microbiota in individuals with prediabetes

  Diabetologia · 2018 · 10.1007/s00125-018-4550-1

• A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links

  Nature Protocols · 2018 · 10.1038/s41596-018-0064-z

• Impact of a vegan diet on the human salivary microbiota

  Scientific Reports · 2018 · 10.1038/s41598-018-24207-3

• A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-07019-x

• Impact of a vegan diet on the human salivary microbiota

  Scientific Reports · 2018 · 10.1038/s41598-018-24207-3

• Recovery of gut microbiota of healthy adults following antibiotic exposure

  Nature Microbiology · 2018 · https://doi.org/10.1038/s41564-018-0257-9

• A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links

  Nature Protocols · 2018 · 10.1038/s41596-018-0064-z

• Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota

  Genome Medicine · 2016 · 10.1186/s13073-016-0312-1

• Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials

  Genome Medicine · 2016 · 10.1186/s13073-016-0300-5

• Human gut microbes impact host serum metabolome and insulin sensitivity

  Nature · 2016 · https://doi.org/10.1038/nature18646

• Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

  Nature · 2015 · https://doi.org/10.1038/nature15766

• Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

  Nature Biotechnology · 2014 · https://doi.org/10.1038/nbt.2939

• MECHANISMS IN ENDOCRINOLOGY: Gut microbiota in patients with type 2 diabetes mellitus

  European Journal of Endocrinology · 2014 · 10.1530/eje-14-0874

• An integrated catalog of reference genes in the human gut microbiome

  Nature Biotechnology · 2014 · https://doi.org/10.1038/nbt.2942

• Richness of human gut microbiome correlates with metabolic markers

  Nature · 2013 · https://doi.org/10.1038/nature12506

• Erratum: Enterotypes of the human gut microbiome

  Nature · 2011 · 10.1038/nature10187

• Erratum: Enterotypes of the human gut microbiome

  Nature · 2011 · 10.1038/nature10187

• Enterotypes of the human gut microbiome

  Nature · 2011 · https://doi.org/10.1038/nature09944

• A human gut microbial gene catalogue established by metagenomic sequencing

  Nature · 2010 · https://doi.org/10.1038/nature08821

• The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

  Diabetologia · 2007 · 10.1007/s00125-007-0865-z

• The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

  Diabetologia · 2007 · 10.1007/s00125-007-0865-z

Current projects

No projects listed.