Juleen R. Zierath

Research interests

Publications

• Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine

  Civil War Book Review · 2022

• Exerkines in health, resilience and disease

  Nature Reviews Endocrinology · 2022 · https://doi.org/10.1038/s41574-022-00641-2

• Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

  Nature Communications · 2020 · 10.1038/s41467-019-13869-w

• Circadian rhythms and exercise — re-setting the clock in metabolic disease

  Nature Reviews Endocrinology · 2019 · 10.1038/s41574-018-0150-x

• Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

  PLoS Medicine · 2016 · 10.1371/journal.pmed.1002179

• Exercise Promotes Healthy Aging of Skeletal Muscle

  Cell Metabolism · 2016 · 10.1016/j.cmet.2016.05.007

• Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans

  Cell Metabolism · 2015 · 10.1016/j.cmet.2015.11.004

• High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring

  Molecular Metabolism · 2015 · 10.1016/j.molmet.2015.12.002

• A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

  Nature · 2014 · 10.1038/nature13425

• Integrative Biology of Exercise

  Cell · 2014 · https://doi.org/10.1016/j.cell.2014.10.029

• Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

  Cell · 2014 · 10.1016/j.cell.2014.07.051

• Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

  Cell Metabolism · 2013 · https://doi.org/10.1016/j.cmet.2012.12.012

• Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

  Cell Metabolism · 2012 · https://doi.org/10.1016/j.cmet.2012.01.001

• Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle

  The Journal of Physiology · 2010 · 10.1113/jphysiol.2010.188011

• Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

  Cell Metabolism · 2010 · https://doi.org/10.1016/j.cmet.2010.02.006

• Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density

  Cell Metabolism · 2009 · 10.1016/j.cmet.2009.07.011

• TXNIP Regulates Peripheral Glucose Metabolism in Humans

  PLoS Medicine · 2007 · 10.1371/journal.pmed.0040158

• Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver

  Diabetologia · 2006 · 10.1007/s00125-005-0105-3

• Tumor Necrosis Factor-α Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation

  Diabetes · 2005 · 10.2337/diabetes.54.10.2939

• Skeletal Muscle Fiber Type: Influence on Contractile and Metabolic Properties

  PLoS Biology · 2004 · 10.1371/journal.pbio.0020348

• Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism

  Journal of Biological Chemistry · 2003 · 10.1074/jbc.m212754200

• Insulin action and insulin resistance in human skeletal muscle

  Diabetologia · 2000 · 10.1007/s001250051457

• Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients.

  Diabetes · 2000 · 10.2337/diabetes.49.2.284

• Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

  Science · 1999 · 10.1126/science.284.5416.974

• Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM

  Diabetologia · 1996 · 10.1007/bf02658504

Current projects

No projects listed.