Timothy R. Walsh

Research interests

Publications

• Antimicrobial Resistance: Addressing a Global Threat to Humanity

  PLoS Medicine · 2023 · 10.1371/journal.pmed.1004264

• Changes in colistin resistance and mcr-1 abundance in Escherichia coli of animal and human origins following the ban of colistin-positive additives in China: an epidemiological comparative study

  The Lancet Infectious Diseases · 2020 · 10.1016/s1473-3099(20)30149-3

• Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans

  Nature Microbiology · 2019 · https://doi.org/10.1038/s41564-019-0445-2

• Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis

  The Lancet Planetary Health · 2018 · 10.1016/s2542-5196(18)30186-4

• Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

  The Lancet Respiratory Medicine · 2018 · https://doi.org/10.1016/s2213-2600(18)30177-2

• Prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive Enterobacteriaceae in patients and healthy adults from China: an epidemiological and clinical study

  The Lancet Infectious Diseases · 2017 · 10.1016/s1473-3099(16)30527-8

• Novel Plasmid-Mediated Colistin Resistance Gene mcr-3 in Escherichia coli

  mBio · 2017 · 10.1128/mbio.00543-17

• Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production

  Nature Microbiology · 2017 · 10.1038/nmicrobiol.2016.260

• Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study

  The Lancet Infectious Diseases · 2016 · https://doi.org/10.1016/s1473-3099(16)30257-2

• Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

  The Lancet Infectious Diseases · 2015 · https://doi.org/10.1016/s1473-3099(15)00424-7

• Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance

  Nature · 2014 · 10.1038/nature13445

• Global dissemination of a multidrug resistant Escherichia coli clone

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1322678111

• The emerging NDM carbapenemases

  Trends in Microbiology · 2011 · 10.1016/j.tim.2011.09.005

• Multiplex PCR for detection of acquired carbapenemase genes

  Diagnostic Microbiology and Infectious Disease · 2011 · 10.1016/j.diagmicrobio.2010.12.002

• Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study

  The Lancet Infectious Diseases · 2011 · 10.1016/s1473-3099(11)70059-7

• Tackling antibiotic resistance

  Nature Reviews Microbiology · 2011 · 10.1038/nrmicro2693

• Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

  The Lancet Infectious Diseases · 2010 · 10.1016/s1473-3099(10)70143-2

• Emerging carbapenemases: a global perspective

  International Journal of Antimicrobial Agents · 2010 · 10.1016/s0924-8579(10)70004-2

• How To Detect NDM-1 Producers

  Journal of Clinical Microbiology · 2010 · 10.1128/jcm.01773-10

• Characterization of a New Metallo-β-Lactamase Gene, bla NDM-1 , and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

  Antimicrobial Agents and Chemotherapy · 2009 · 10.1128/aac.00774-09

• Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India

  · 2009

• IS CR Elements: Novel Gene-Capturing Systems of the 21st Century?

  Microbiology and Molecular Biology Reviews · 2006 · 10.1128/mmbr.00048-05

• Metallo-β-Lactamases: the Quiet before the Storm?

  Clinical Microbiology Reviews · 2005 · 10.1128/cmr.18.2.306-325.2005

• Use of antimicrobial agents in veterinary medicine and food animal production

  International Journal of Antimicrobial Agents · 2001 · 10.1016/s0924-8579(01)00297-7

• The crystal structure of the L1 metallo-β-lactamase from Stenotrophomonas maltophilia at 1.7 å resolution 1 1Edited by K. Nagai

  Journal of Molecular Biology · 1998 · 10.1006/jmbi.1998.2148

Current projects

No projects listed.