Jo Vandesompele

Research interests

Publications

• Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction

  Gut · 2018 · https://doi.org/10.1136/gutjnl-2018-317726

• A mechanistic classification of clinical phenotypes in neuroblastoma

  Science · 2018 · https://doi.org/10.1126/science.aat6768

• EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

  Nature Methods · 2017 · https://doi.org/10.1038/nmeth.4185

• Melanoma addiction to the long non-coding RNA SAMMSON

  Nature · 2016 · https://doi.org/10.1038/nature17161

• Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

  Genome biology · 2015 · https://doi.org/10.1186/s13059-015-0694-1

• The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling

  Journal of Extracellular Vesicles · 2014 · https://doi.org/10.3402/jev.v3.24858

• A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

  Nature Biotechnology · 2014 · https://doi.org/10.1038/nbt.2957

• The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments

  Clinical Chemistry · 2013 · https://doi.org/10.1373/clinchem.2013.206375

• The need for transparency and good practices in the qPCR literature

  Nature Methods · 2013 · https://doi.org/10.1038/nmeth.2697

• Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2396

• miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis

  Nature Cell Biology · 2010 · https://doi.org/10.1038/ncb2024

• Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

  Clinical Cancer Research · 2010 · https://doi.org/10.1158/1078-0432.ccr-09-2660

• Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

  Nucleic Acids Research · 2010 · https://doi.org/10.1093/nar/gkq342

• Amphiregulin and Epiregulin mRNA Expression in Primary Tumors Predicts Outcome in Metastatic Colorectal Cancer Treated With Cetuximab

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2008.21.3744

• The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

  Clinical Chemistry · 2009 · https://doi.org/10.1373/clinchem.2008.112797

• Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study

  The Lancet Oncology · 2009 · https://doi.org/10.1016/s1470-2045(09)70154-8

• qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

  Genome biology · 2007 · https://doi.org/10.1186/gb-2007-8-2-r19

• Unequivocal Delineation of Clinicogenetic Subgroups and Development of a New Model for Improved Outcome Prediction in Neuroblastoma

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.06.104

• Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

  Nature Genetics · 2004 · https://doi.org/10.1038/ng1453

• Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

  Genome biology · 2002 · https://doi.org/10.1186/gb-2002-3-7-research0034

Current projects

No projects listed.