Juergen A. Knoblich

Research interests

Publications

• Human organoids: model systems for human biology and medicine

  Nature Reviews Molecular Cell Biology · 2020 · https://doi.org/10.1038/s41580-020-0259-3

• Human blood vessel organoids as a model of diabetic vasculopathy

  Nature · 2019 · https://doi.org/10.1038/s41586-018-0858-8

• Genetically engineered cerebral organoids model brain tumor formation

  Nature Methods · 2018 · 10.1038/s41592-018-0070-7

• The hope and the hype of organoid research

  Development · 2017 · 10.1242/dev.150201

• Fused cerebral organoids model interactions between brain regions

  Nature Methods · 2017 · 10.1038/nmeth.4304

• Guided self-organization and cortical plate formation in human brain organoids

  Nature Biotechnology · 2017 · 10.1038/nbt.3906

• Self‐organized developmental patterning and differentiation in cerebral organoids

  The EMBO Journal · 2017 · 10.15252/embj.201694700

• Induction of Expansion and Folding in Human Cerebral Organoids

  Cell stem cell · 2016 · 10.1016/j.stem.2016.11.017

• Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

  Proceedings of the National Academy of Sciences · 2015 · https://doi.org/10.1073/pnas.1520760112

• Proliferation control in neural stem and progenitor cells

  Nature reviews. Neuroscience · 2015 · 10.1038/nrn4021

• Organogenesis in a dish: Modeling development and disease using organoid technologies

  Science · 2014 · https://doi.org/10.1126/science.1247125

• Generation of cerebral organoids from human pluripotent stem cells

  Nature Protocols · 2014 · https://doi.org/10.1038/nprot.2014.158

• Cerebral organoids model human brain development and microcephaly

  Nature · 2013 · https://doi.org/10.1038/nature12517

• Drosophila neuroblasts: a model for stem cell biology

  Development · 2012 · 10.1242/dev.080515

• Asymmetric cell division: recent developments and their implications for tumour biology

  Nature Reviews Molecular Cell Biology · 2010 · 10.1038/nrm3010

• The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

  Cell · 2009 · 10.1016/j.cell.2008.12.024

• Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer

  Genes & Development · 2009 · 10.1101/gad.1850809

• The Tumor Suppressors Brat and Numb Regulate Transit-Amplifying Neuroblast Lineages in Drosophila

  Developmental Cell · 2008 · 10.1016/j.devcel.2008.03.004

• Mechanisms of Asymmetric Stem Cell Division

  Cell · 2008 · 10.1016/j.cell.2008.02.007

• Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells

  Cell · 2006 · 10.1016/j.cell.2006.01.038

• Dare to Be Different: Asymmetric Cell Division in Drosophila, C. elegans and Vertebrates

  Current Biology · 2004 · 10.1016/j.cub.2004.08.017

• The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl

  Nature · 2003 · 10.1038/nature01486

• DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

  Nature Cell Biology · 2000 · 10.1038/35050550

• Asymmetric segregation of Numb and Prospero during cell division

  Nature · 1995 · 10.1038/377624a0

• Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

  Cell · 1994 · 10.1016/0092-8674(94)90239-9

Current projects

No projects listed.