Bart N. Lambrecht

Research interests

Publications

• Local immune response to food antigens drives meal-induced abdominal pain

  Nature · 2021 · https://doi.org/10.1038/s41586-020-03118-2

• The basic immunology of asthma

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.02.016

• Adult chronic rhinosinusitis

  Nature Reviews Disease Primers · 2020 · https://doi.org/10.1038/s41572-020-00218-1

• The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

  Immunity · 2018 · https://doi.org/10.1016/j.immuni.2018.07.004

• Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

  Journal of Allergy and Clinical Immunology · 2017 · https://doi.org/10.1016/j.jaci.2016.12.940

• Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung

  Immunity · 2016 · https://doi.org/10.1016/j.immuni.2016.10.031

• Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages

  Immunity · 2016 · https://doi.org/10.1016/j.immuni.2016.02.017

• Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

  Immunity · 2016 · https://doi.org/10.1016/j.immuni.2016.08.015

• FlowSOM: Using self‐organizing maps for visualization and interpretation of cytometry data

  Cytometry Part A · 2015 · https://doi.org/10.1002/cyto.a.22625

• Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

  Science · 2015 · https://doi.org/10.1126/science.aac6623

• Are allergic multimorbidities and IgE polysensitization associated with the persistence or re‐occurrence of foetal type 2 signalling? The M e DALL hypothesis

  Allergy · 2015 · https://doi.org/10.1111/all.12637

• The immunology of asthma

  Nature Immunology · 2014 · https://doi.org/10.1038/ni.3049

• Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

  The Journal of Experimental Medicine · 2013 · https://doi.org/10.1084/jem.20131199

• Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

  Immunity · 2013 · https://doi.org/10.1016/j.immuni.2012.10.016

• Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33

  The Journal of Experimental Medicine · 2012 · https://doi.org/10.1084/jem.20112691

• The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

  Immunity · 2011 · https://doi.org/10.1016/j.immuni.2011.05.013

• Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

  Trends in Immunology · 2011 · https://doi.org/10.1016/j.it.2011.01.005

• A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.874

• House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

  Nature Medicine · 2009 · https://doi.org/10.1038/nm.1946

• Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

  The Journal of Experimental Medicine · 2008 · https://doi.org/10.1084/jem.20071087

• In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma

  The Journal of Experimental Medicine · 2005 · https://doi.org/10.1084/jem.20042311

Current projects

No projects listed.