Anton Berns

Research interests

Publications

• Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

  Cell · 2013 · 10.1016/j.cell.2013.07.018

• Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

  Cancer Cell · 2011 · 10.1016/j.ccr.2011.04.019

• A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer

  Cancer Cell · 2011 · 10.1016/j.ccr.2010.12.021

• For better or for worse: the role of Pim oncogenes in tumorigenesis

  Nature reviews. Cancer · 2010 · 10.1038/nrc2986

• Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1 -mutated basal-like breast cancer

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0702969104

• Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis

  Cancer Cell · 2006 · 10.1016/j.ccr.2006.09.013

• Mouse models for human lung cancer

  Genes & Development · 2005 · 10.1101/gad.1284505

• Mice Deficient for All PIM Kinases Display Reduced Body Size and Impaired Responses to Hematopoietic Growth Factors

  Molecular and Cellular Biology · 2004 · 10.1128/mcb.24.13.6104-6115.2004

• Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

  Cancer Cell · 2003 · 10.1016/s1535-6108(03)00220-4

• High-throughput retroviral tagging to identify components of specific signaling pathways in cancer

  Nature Genetics · 2002 · 10.1038/ng950

• Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.161269798

• A highly efficient ligand‐regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

  EMBO Reports · 2001 · 10.1093/embo-reports/kve064

• Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

  Genes & Development · 1999 · https://doi.org/10.1101/gad.13.20.2678

• p107 is a suppressor of retinoblastoma development in pRb-deficient mice

  Genes & Development · 1998 · 10.1101/gad.12.11.1599

• Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex–Encoded Molecules

  The Journal of Experimental Medicine · 1997 · 10.1084/jem.186.8.1269

• Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice

  Nature Genetics · 1996 · 10.1038/ng0796-316

• Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

  Cell · 1994 · https://doi.org/10.1016/0092-8674(94)90212-7

• Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

  Cell · 1993 · https://doi.org/10.1016/0092-8674(93)90380-9

• Requirement for a functional Rb-1 gene in murine development

  Nature · 1992 · https://doi.org/10.1038/359328a0

• Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.

  Proceedings of the National Academy of Sciences · 1992 · 10.1073/pnas.89.11.5128

• The pim‐1 oncogene encodes two related protein‐serine/threonine kinases by alternative initiation at AUG and CUG.

  The EMBO Journal · 1991 · 10.1002/j.1460-2075.1991.tb07994.x

• Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging

  Cell · 1991 · https://doi.org/10.1016/0092-8674(91)90382-9

• Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

  Cell · 1989 · 10.1016/0092-8674(89)90589-8

• In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes

  Cell · 1988 · 10.1016/0092-8674(88)90425-4

• Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

  Cell · 1984 · 10.1016/0092-8674(84)90309-x

Current projects

No projects listed.