Richard Smith

Research interests

Publications

• Proteogenomic data and resources for pan-cancer analysis

  Cancer Cell · 2023 · https://doi.org/10.1016/j.ccell.2023.06.009

• Proteogenomic and metabolomic characterization of human glioblastoma

  Cancer Cell · 2021 · https://doi.org/10.1016/j.ccell.2021.01.006

• High-throughput and high-efficiency sample preparation for single-cell proteomics using a nested nanowell chip

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-26514-2

• Proteogenomic Characterization of Endometrial Carcinoma

  Cell · 2020 · 10.1016/j.cell.2020.01.026

• Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.10.044

• Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy

  Cell · 2020 · 10.1016/j.cell.2020.10.036

• Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.03.030

• Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells

  Nature Communications · 2018 · 10.1038/s41467-018-03367-w

• Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography–mass spectrometry

  Nature Protocols · 2018 · 10.1038/s41596-018-0006-9

• Multi-platform ’Omics Analysis of Human Ebola Virus Disease Pathogenesis

  Cell Host & Microbe · 2017 · https://doi.org/10.1016/j.chom.2017.10.011

• LIQUID: an-open source software for identifying lipids in LC-MS/MS-based lipidomics data

  Bioinformatics · 2017 · https://doi.org/10.1093/bioinformatics/btx046

• An Interlaboratory Evaluation of Drift Tube Ion Mobility–Mass Spectrometry Collision Cross Section Measurements

  Analytical Chemistry · 2017 · 10.1021/acs.analchem.7b01729

• MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses

  mSystems · 2016 · https://doi.org/10.1128/msystems.00043-16

• Uncovering biologically significant lipid isomers with liquid chromatography, ion mobility spectrometry and mass spectrometry

  The Analyst · 2016 · https://doi.org/10.1039/c5an02062j

• Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.05.069

• Genomic responses in mouse models poorly mimic human inflammatory diseases

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1222878110

• Activated ClpP kills persisters and eradicates a chronic biofilm infection

  Nature · 2013 · 10.1038/nature12790

• Reversed‐phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells

  PROTEOMICS · 2011 · 10.1002/pmic.201000722

• Comparative Analysis of Proteome and Transcriptome Variation in Mouse

  PLoS Genetics · 2011 · 10.1371/journal.pgen.1001393

• Establishing the Proteome of Normal Human Cerebrospinal Fluid

  PLoS ONE · 2010 · https://doi.org/10.1371/journal.pone.0010980

• Omic data from evolved E. coli are consistent with computed optimal growth from genome‐scale models

  Molecular Systems Biology · 2010 · https://doi.org/10.1038/msb.2010.47

• Fundamentals of Traveling Wave Ion Mobility Spectrometry

  Analytical Chemistry · 2008 · 10.1021/ac8016295

• VIPER: an advanced software package to support high-throughput LC-MS peptide identification

  Bioinformatics · 2007 · https://doi.org/10.1093/bioinformatics/btm281

• Normalization Approaches for Removing Systematic Biases Associated with Mass Spectrometry and Label-Free Proteomics

  Journal of Proteome Research · 2006 · 10.1021/pr050300l

• Automated 20 kpsi RPLC-MS and MS/MS with Chromatographic Peak Capacities of 1000−1500 and Capabilities in Proteomics and Metabolomics

  Analytical Chemistry · 2005 · https://doi.org/10.1021/ac0483062

• Identification of Proteins in Human Cytomegalovirus (HCMV) Particles: the HCMV Proteome

  Journal of Virology · 2004 · 10.1128/jvi.78.20.10960-10966.2004

• A common open representation of mass spectrometry data and its application to proteomics research

  Nature Biotechnology · 2004 · 10.1038/nbt1031

• Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags

  Proceedings of the National Academy of Sciences · 2002 · https://doi.org/10.1073/pnas.172170199

• Toward a Human Blood Serum Proteome

  Molecular & Cellular Proteomics · 2002 · 10.1074/mcp.m200066-mcp200

• High Throughput Proteome-Wide Precision Measurements of Protein Expression Using Mass Spectrometry

  Journal of the American Chemical Society · 1999 · https://doi.org/10.1021/ja991063o

• PHYTOREMEDIATION

  Annual Review of Plant Physiology and Plant Molecular Biology · 1998 · 10.1146/annurev.arplant.49.1.643

• Principles and practice of electrospray ionization—mass spectrometry for large polypeptides and proteins

  Mass Spectrometry Reviews · 1991 · 10.1002/mas.1280100504

• New developments in biochemical mass spectrometry: electrospray ionization

  Analytical Chemistry · 1990 · 10.1021/ac00208a002

• [22] Electrospray ionization mass spectrometry

  Methods in enzymology on CD-ROM/Methods in enzymology · 1990 · 10.1016/0076-6879(90)93430-s

• Improved electrospray ionization interface for capillary zone electrophoresis-mass spectrometry

  Analytical Chemistry · 1988 · 10.1021/ac00169a022

• On-line mass spectrometric detection for capillary zone electrophoresis

  Analytical Chemistry · 1987 · 10.1021/ac00135a034

Current projects

No projects listed.