Peter V. Kharchenko

Research interests

Publications

• An atlas of healthy and injured cell states and niches in the human kidney

  Nature · 2023 · https://doi.org/10.1038/s41586-023-05769-3

• Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2

  Genome biology · 2021 · https://doi.org/10.1186/s13059-021-02267-5

• Comparative cellular analysis of motor cortex in human, marmoset and mouse

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03465-8

• A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03500-8

• Cell segmentation in imaging-based spatial transcriptomics

  Nature Biotechnology · 2021 · https://doi.org/10.1038/s41587-021-01044-w

• Spatiotemporal structure of cell fate decisions in murine neural crest

  Science · 2019 · https://doi.org/10.1126/science.aas9536

• The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1629-x

• RNA velocity of single cells

  Nature · 2018 · https://doi.org/10.1038/s41586-018-0414-6

• Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain

  Nature Biotechnology · 2017 · https://doi.org/10.1038/nbt.4038

• Challenges and emerging directions in single-cell analysis

  Genome biology · 2017 · 10.1186/s13059-017-1218-y

• Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla

  Science · 2017 · 10.1126/science.aal3753

• Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.07.025

• Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

  Science · 2016 · https://doi.org/10.1126/science.aad3312

• Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis

  Nature Methods · 2016 · https://doi.org/10.1038/nmeth.3734

• Comparative analysis of metazoan chromatin organization

  Nature · 2014 · https://doi.org/10.1038/nature13415

• Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

  Nature Neuroscience · 2014 · https://doi.org/10.1038/nn.3881

• Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia

  Cancer Cell · 2014 · https://doi.org/10.1016/j.ccell.2014.10.012

• Bayesian approach to single-cell differential expression analysis

  Nature Methods · 2014 · https://doi.org/10.1038/nmeth.2967

• ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

  Genome Research · 2012 · 10.1101/gr.136184.111

• Landscape of Somatic Retrotransposition in Human Cancers

  Science · 2012 · https://doi.org/10.1126/science.1222077

• The genomic binding sites of a noncoding RNA

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1113536108

• Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

  Science · 2010 · 10.1126/science.1198374

• Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

  Nature · 2010 · 10.1038/nature09725

• An assessment of histone-modification antibody quality

  Nature Structural & Molecular Biology · 2010 · https://doi.org/10.1038/nsmb.1972

• Design and analysis of ChIP-seq experiments for DNA-binding proteins

  Nature Biotechnology · 2008 · https://doi.org/10.1038/nbt.1508

Current projects

No projects listed.