Arun Sharma

Research interests

Publications

• Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

  Circulation · 2020 · https://doi.org/10.1161/circulationaha.119.042339

• Human-Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Patients With Breast Cancer

  Circulation · 2019 · https://doi.org/10.1161/circulationaha.118.037357

• Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-07333-4

• High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells

  Science Translational Medicine · 2017 · https://doi.org/10.1126/scitranslmed.aaf2584

• Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4087

• Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell–Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome

  Journal of the American College of Cardiology · 2016 · https://doi.org/10.1016/j.jacc.2016.07.779

• Screening Drug-Induced Arrhythmia Using Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes and Low-Impedance Microelectrode Arrays

  Circulation · 2013 · https://doi.org/10.1161/circulationaha.112.000570

• Mutations at the BLK locus linked to maturity onset diabetes of the young and β-cell dysfunction

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0906474106

• In vitro cultivation of human islets from expanded ductal tissue

  Proceedings of the National Academy of Sciences · 2000 · https://doi.org/10.1073/pnas.97.14.7999

Current projects

No projects listed.