Jonathan S. Gootenberg
Researcher Next ID · RN-021805
Researcher · Biochemistry, Genetics and Molecular Biology
Boston, Israel
- Works count
- 119
- Citation count
- 46,182
- H-index
- 49
- i10-index
- 68
Research interests
Publications
A global metagenomic map of urban microbiomes and antimicrobial resistance
Cell · 2021 · https://doi.org/10.1016/j.cell.2021.05.002
CRISPR-based diagnostics
Nature Biomedical Engineering · 2021 · https://doi.org/10.1038/s41551-021-00760-7
Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA
Nature Biomedical Engineering · 2020 · https://doi.org/10.1038/s41551-020-00603-x
Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing
New England Journal of Medicine · 2020 · https://doi.org/10.1056/nejmc2026172
SHERLOCK: nucleic acid detection with CRISPR nucleases
Nature Protocols · 2019 · https://doi.org/10.1038/s41596-019-0210-2
Engineered CRISPR-Cas9 nuclease with expanded targeting space
Science · 2018 · https://doi.org/10.1126/science.aas9129
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
Science · 2018 · https://doi.org/10.1126/science.aaq0179
Field-deployable viral diagnostics using CRISPR-Cas13
Science · 2018 · https://doi.org/10.1126/science.aas8836
Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
Nature Protocols · 2017 · https://doi.org/10.1038/nprot.2017.016
RNA targeting with CRISPR–Cas13
Nature · 2017 · https://doi.org/10.1038/nature24049
Diversity and evolution of class 2 CRISPR–Cas systems
Nature Reviews Microbiology · 2017 · https://doi.org/10.1038/nrmicro.2016.184
RNA editing with CRISPR-Cas13
Science · 2017 · https://doi.org/10.1126/science.aaq0180
Nucleic acid detection with CRISPR-Cas13a/C2c2
Science · 2017 · https://doi.org/10.1126/science.aam9321
Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28
Molecular Cell · 2017 · https://doi.org/10.1016/j.molcel.2016.12.023
Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
Nature Biotechnology · 2016 · https://doi.org/10.1038/nbt.3737
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
Science · 2016 · https://doi.org/10.1126/science.aaf5573
Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems
Molecular Cell · 2015 · https://doi.org/10.1016/j.molcel.2015.10.008
In vivo genome editing using Staphylococcus aureus Cas9
Nature · 2015 · https://doi.org/10.1038/nature14299
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Cell · 2015 · 10.1016/j.cell.2015.09.038
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Nature · 2014 · https://doi.org/10.1038/nature14136
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
Cell · 2013 · https://doi.org/10.1016/j.cell.2013.08.021
Current projects
No projects listed.