Iacopo Olivotto

Research interests

Publications

• Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy

  New England Journal of Medicine · 2024 · https://doi.org/10.1056/nejmoa2401424

• 2023 ESC Guidelines for the management of cardiomyopathies

  European Heart Journal · 2023 · https://doi.org/10.1093/eurheartj/ehad194

• Acute Myocarditis Associated With Desmosomal Gene Variants

  JACC Heart Failure · 2022 · https://doi.org/10.1016/j.jchf.2022.06.013

• Cardiac Involvement in Fabry Disease

  Journal of the American College of Cardiology · 2021 · 10.1016/j.jacc.2020.12.024

• An Expert Consensus Document on the Management of Cardiovascular Manifestations of Fabry Disease

  European Journal of Heart Failure · 2020 · https://doi.org/10.1002/ejhf.1960

• Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial

  The Lancet · 2020 · https://doi.org/10.1016/s0140-6736(20)31792-x

• Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

  Circulation · 2020 · 10.1161/circulationaha.119.042339

• Development of a Novel Risk Prediction Model for Sudden Cardiac Death in Childhood Hypertrophic Cardiomyopathy (HCM Risk-Kids)

  JAMA Cardiology · 2019 · https://doi.org/10.1001/jamacardio.2019.2861

• Distinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry

  Journal of the American College of Cardiology · 2019 · 10.1016/j.jacc.2019.08.1057

• Recommendations for participation in competitive and leisure time sport in athletes with cardiomyopathies, myocarditis, and pericarditis: position statement of the Sport Cardiology Section of the European Association of Preventive Cardiology (EAPC)

  European Heart Journal · 2018 · 10.1093/eurheartj/ehy730

• Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy

  Circulation · 2018 · 10.1161/circulationaha.117.033200

• International External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM)

  Circulation · 2017 · https://doi.org/10.1161/circulationaha.117.030437

• Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study

  Journal of Medical Genetics · 2016 · 10.1136/jmedgenet-2016-104178

• Prognostic Value of Quantitative Contrast-Enhanced Cardiovascular Magnetic Resonance for the Evaluation of Sudden Death Risk in Patients With Hypertrophic Cardiomyopathy

  Circulation · 2014 · 10.1161/circulationaha.113.007094

• Hypertrophic Cardiomyopathy

  Journal of the American College of Cardiology · 2014 · 10.1016/j.jacc.2014.05.003

• Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy

  Circulation · 2012 · 10.1161/circulationaha.112.134932

• Patterns of Disease Progression in Hypertrophic Cardiomyopathy

  Circulation Heart Failure · 2012 · 10.1161/circheartfailure.112.967026

• Mitral Valve Abnormalities Identified by Cardiovascular Magnetic Resonance Represent a Primary Phenotypic Expression of Hypertrophic Cardiomyopathy

  Circulation · 2011 · 10.1161/circulationaha.110.985812

• Hypertrophic Cardiomyopathy Phenotype Revisited After 50 Years With Cardiovascular Magnetic Resonance

  Journal of the American College of Cardiology · 2009 · 10.1016/j.jacc.2009.05.006

• Assessment and Significance of Left Ventricular Mass by Cardiovascular Magnetic Resonance in Hypertrophic Cardiomyopathy

  Journal of the American College of Cardiology · 2008 · 10.1016/j.jacc.2008.04.047

• Hypertrophic Cardiomyopathy Is Predominantly a Disease of Left Ventricular Outflow Tract Obstruction

  Circulation · 2006 · https://doi.org/10.1161/circulationaha.106.644682

• Gender-Related Differences in the Clinical Presentation and Outcome of Hypertrophic Cardiomyopathy

  Journal of the American College of Cardiology · 2005 · 10.1016/j.jacc.2005.04.043

• Long-Term Effects of Surgical Septal Myectomy on Survival in Patients With Obstructive Hypertrophic Cardiomyopathy

  Journal of the American College of Cardiology · 2005 · 10.1016/j.jacc.2005.02.090

• Coronary Microvascular Dysfunction and Prognosis in Hypertrophic Cardiomyopathy

  New England Journal of Medicine · 2003 · 10.1056/nejmoa025050

• Effect of Left Ventricular Outflow Tract Obstruction on Clinical Outcome in Hypertrophic Cardiomyopathy

  New England Journal of Medicine · 2003 · https://doi.org/10.1056/nejmoa021332

• Clinical profile of stroke in 900 patients with hypertrophic cardiomyopathy

  Journal of the American College of Cardiology · 2002 · 10.1016/s0735-1097(01)01727-2

• Impact of Atrial Fibrillation on the Clinical Course of Hypertrophic Cardiomyopathy

  Circulation · 2001 · 10.1161/hc4601.097997

• Epidemiology of Hypertrophic Cardiomyopathy–Related Death

  Circulation · 2000 · 10.1161/01.cir.102.8.858

• Short-Term Clinical Outcome of Patients With Acute Pulmonary Embolism, Normal Blood Pressure, and Echocardiographic Right Ventricular Dysfunction

  Circulation · 2000 · 10.1161/01.cir.101.24.2817

Current projects

No projects listed.