Peter Libby

Research interests

Publications

• Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

  New England Journal of Medicine · 2023 · https://doi.org/10.1056/nejmoa2215024

• The changing landscape of atherosclerosis

  Nature · 2021 · 10.1038/s41586-021-03392-8

• IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial

  The Lancet · 2021 · https://doi.org/10.1016/s0140-6736(21)00520-1

• COVID-19 is, in the end, an endothelial disease

  European Heart Journal · 2020 · https://doi.org/10.1093/eurheartj/ehaa623

• Atherosclerosis

  Nature Reviews Disease Primers · 2019 · https://doi.org/10.1038/s41572-019-0106-z

• Reassessing the Mechanisms of Acute Coronary Syndromes

  Circulation Research · 2019 · https://doi.org/10.1161/circresaha.118.311098

• Low-Dose Methotrexate for the Prevention of Atherosclerotic Events

  New England Journal of Medicine · 2018 · 10.1056/nejmoa1809798

• Macrophages Facilitate Electrical Conduction in the Heart

  Cell · 2017 · 10.1016/j.cell.2017.03.050

• The Aging Cardiovascular System

  Journal of the American College of Cardiology · 2017 · 10.1016/j.jacc.2017.01.064

• A guiding map for inflammation

  Nature Immunology · 2017 · 10.1038/ni.3790

• Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

  New England Journal of Medicine · 2017 · 10.1056/nejmoa1701719

• Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy

  New England Journal of Medicine · 2013 · 10.1056/nejmra1216063

• Local proliferation dominates lesional macrophage accumulation in atherosclerosis

  Nature Medicine · 2013 · 10.1038/nm.3258

• Myocardial infarction accelerates atherosclerosis

  Nature · 2012 · 10.1038/nature11260

• Inflammation in Atherosclerosis

  Arteriosclerosis Thrombosis and Vascular Biology · 2012 · 10.1161/atvbaha.108.179705

• Progress and challenges in translating the biology of atherosclerosis

  Nature · 2011 · https://doi.org/10.1038/nature10146

• Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine

  Medical Entomology and Zoology · 2011

• Inflammation in Atherosclerosis

  Journal of the American College of Cardiology · 2009 · 10.1016/j.jacc.2009.09.009

• Rosuvastatin to Prevent Vascular Events in Men and Women With Elevated C-Reactive Protein

  Obstetrical & Gynecological Survey · 2009 · 10.1097/01.ogx.0000344393.60303.0a

• Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

  Science · 2009 · 10.1126/science.1175202

• Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

  New England Journal of Medicine · 2008 · https://doi.org/10.1056/nejmoa0807646

• The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

  The Journal of Experimental Medicine · 2007 · 10.1084/jem.20070885

• Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

  Journal of Clinical Investigation · 2007 · 10.1172/jci29950

• The immune response in atherosclerosis: a double-edged sword

  Nature reviews. Immunology · 2006 · 10.1038/nri1882

• Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis

  JAMA · 2006 · 10.1001/jama.295.13.jpc60002

• Pathophysiology of Coronary Artery Disease

  Circulation · 2005 · 10.1161/circulationaha.105.537878

• Effect of Antihypertensive Agents on Cardiovascular Events in Patients With Coronary Disease and Normal Blood Pressure

  JAMA · 2004 · 10.1001/jama.292.18.2217

• From Vulnerable Plaque to Vulnerable Patient

  Circulation · 2003 · 10.1161/01.cir.0000087481.55887.c9

• From Vulnerable Plaque to Vulnerable Patient

  Circulation · 2003 · 10.1161/01.cir.0000087480.94275.97

• Diabetes and Atherosclerosis

  JAMA · 2002 · 10.1001/jama.287.19.2570

• Inflammation and Atherosclerosis

  Circulation · 2002 · https://doi.org/10.1161/hc0902.104353

• Inflammation in atherosclerosis

  Nature · 2002 · https://doi.org/10.1038/nature01323

• Current Concepts of the Pathogenesis of the Acute Coronary Syndromes

  Circulation · 2001 · 10.1161/01.cir.104.3.365

• Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes

  American Journal Of Pathology · 2001 · 10.1016/s0002-9440(10)64036-9

• Absence of Monocyte Chemoattractant Protein-1 Reduces Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

  Molecular Cell · 1998 · 10.1016/s1097-2765(00)80139-2

• Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

  Journal of Clinical Investigation · 1995 · 10.1172/jci118074

• Molecular Bases of the Acute Coronary Syndromes

  Circulation · 1995 · 10.1161/01.cir.91.11.2844

Current projects

No projects listed.