Sarah K. Highlander

Research interests

Publications

• Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial

  Nature Medicine · 2022 · 10.1038/s41591-022-01694-6

• Stool Microbiome Profiling of Patients with Metastatic Renal Cell Carcinoma Receiving Anti–PD-1 Immune Checkpoint Inhibitors

  European Urology · 2020 · 10.1016/j.eururo.2020.07.011

• Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

  Cell Metabolism · 2017 · https://doi.org/10.1016/j.cmet.2017.04.001

• Host Genetic Control of the Oral Microbiome in Health and Disease

  Cell Host & Microbe · 2017 · 10.1016/j.chom.2017.08.013

• Gastrointestinal microbial populations can distinguish pediatric and adolescent Acute Lymphoblastic Leukemia (ALL) at the time of disease diagnosis

  BMC Genomics · 2016 · 10.1186/s12864-016-2965-y

• Sequencing 16S rRNA gene fragments using the PacBio SMRT DNA sequencing system

  PeerJ · 2016 · 10.7717/peerj.1869

• Gastrointestinal microbial populations can distinguish pediatric and adolescent Acute Lymphoblastic Leukemia (ALL) at the time of disease diagnosis

  BMC Genomics · 2016 · 10.1186/s12864-016-2965-y

• Library preparation methodology can influence genomic and functional predictions in human microbiome research

  Proceedings of the National Academy of Sciences · 2015 · 10.1073/pnas.1519288112

• Characterization of the human gut microbiome during travelers' diarrhea

  Gut Microbes · 2015 · 10.1080/19490976.2015.1019693

• Characterization of the human gut microbiome during travelers' diarrhea

  Gut Microbes · 2015 · 10.1080/19490976.2015.1019693

• Phylogenomics and the Dynamic Genome Evolution of the Genus Streptococcus

  Genome Biology and Evolution · 2014 · 10.1093/gbe/evu048

• Phylogenomics and the Dynamic Genome Evolution of the Genus Streptococcus

  Genome Biology and Evolution · 2014 · 10.1093/gbe/evu048

• Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform

  Applied and Environmental Microbiology · 2013 · https://doi.org/10.1128/aem.01043-13

• A framework for human microbiome research

  Nature · 2012 · https://doi.org/10.1038/nature11209

• Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomes

  BMC Microbiology · 2012 · 10.1186/1471-2180-12-135

• Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomes

  BMC Microbiology · 2012 · 10.1186/1471-2180-12-135

• Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome

  Gastroenterology · 2011 · 10.1053/j.gastro.2011.06.072

• Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons

  Genome Research · 2011 · https://doi.org/10.1101/gr.112730.110

• Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

  Nature Biotechnology · 2011 · https://doi.org/10.1038/nbt.1823

• A Catalog of Reference Genomes from the Human Microbiome

  Science · 2010 · 10.1126/science.1183605

• Comparative Genomics of Gardnerella vaginalis Strains Reveals Substantial Differences in Metabolic and Virulence Potential

  PLoS ONE · 2010 · 10.1371/journal.pone.0012411

• Comparative Genomics of Gardnerella vaginalis Strains Reveals Substantial Differences in Metabolic and Virulence Potential

  PLoS ONE · 2010 · 10.1371/journal.pone.0012411

• Metagenomic Pyrosequencing and Microbial Identification

  Clinical Chemistry · 2009 · 10.1373/clinchem.2008.107565

• Genome Project Standards in a New Era of Sequencing

  Science · 2009 · 10.1126/science.1180614

• Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF

  Genome biology · 2008 · 10.1186/gb-2008-9-7-r110

• Paradoxical DNA Repair and Peroxide Resistance Gene Conservation in Bacillus pumilus SAFR-032

  PLoS ONE · 2007 · 10.1371/journal.pone.0000928

• Paradoxical DNA Repair and Peroxide Resistance Gene Conservation in Bacillus pumilus SAFR-032

  PLoS ONE · 2007 · 10.1371/journal.pone.0000928

• Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus

  BMC Microbiology · 2007 · 10.1186/1471-2180-7-99

• Complete Genome Sequence ofRickettsia typhiand Comparison with Sequences of Other Rickettsiae

  Journal of Bacteriology · 2004 · 10.1128/jb.186.17.5842-5855.2004

• Pasteurella haemolytica leukotoxin induced apoptosis of bovine lymphocytes involves DNA fragmentation1This report represents a portion of a dissertation submitted by the first author as partial fulfillment of the requirements for the Ph.D. degree.1

  Veterinary Microbiology · 1999 · 10.1016/s0378-1135(98)00286-7

• Pasteurella haemolytica leukotoxin induced apoptosis of bovine lymphocytes involves DNA fragmentation1This report represents a portion of a dissertation submitted by the first author as partial fulfillment of the requirements for the Ph.D. degree.1

  Veterinary Microbiology · 1999 · 10.1016/s0378-1135(98)00286-7

Current projects

No projects listed.