David A. Bennett

Research interests

Publications

• Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-019-0695-9

• Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-0815-6

• Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-19737-2

• Single-cell transcriptomic analysis of Alzheimer’s disease

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1195-2

• Diagnosis and Management of Dementia: Review

  JAMA · 2019 · 10.1001/jama.2019.4782

• Religious Orders Study and Rush Memory and Aging Project

  Journal of Alzheimer s Disease · 2018 · 10.3233/jad-179939

• NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease

  Alzheimer s & Dementia · 2018 · https://doi.org/10.1016/j.jalz.2018.02.018

• A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

  Neurology · 2016 · 10.1212/wnl.0000000000002923

• Gene expression elucidates functional impact of polygenic risk for schizophrenia

  Nature Neuroscience · 2016 · 10.1038/nn.4399

• MIND diet slows cognitive decline with aging

  Alzheimer s & Dementia · 2015 · 10.1016/j.jalz.2015.04.011

• Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

  Nature Neuroscience · 2014 · 10.1038/nn.3786

• Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

  Cell · 2013 · 10.1016/j.cell.2013.03.030

• Charting a dynamic DNA methylation landscape of the human genome

  Nature · 2013 · 10.1038/nature12433

• Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

  Journal of Clinical Investigation · 2012 · 10.1172/jci59903

• Vascular Contributions to Cognitive Impairment and Dementia

  Stroke · 2011 · https://doi.org/10.1161/str.0b013e3182299496

• Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

  Alzheimer s & Dementia · 2011 · https://doi.org/10.1016/j.jalz.2011.03.003

• Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

  Nature Genetics · 2010 · 10.1038/ng.536

• Loneliness and Risk of Alzheimer Disease

  Archives of General Psychiatry · 2007 · 10.1001/archpsyc.64.2.234

• Mixed brain pathologies account for most dementia cases in community-dwelling older persons

  Neurology · 2007 · 10.1212/01.wnl.0000271090.28148.24

• Neuropathology of older persons without cognitive impairment from two community-based studies

  Neurology · 2006 · 10.1212/01.wnl.0000219668.47116.e6

• Mild cognitive impairment

  The Lancet · 2006 · https://doi.org/10.1016/s0140-6736(06)68542-5

• Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive Function

  Archives of Neurology · 2004 · 10.1001/archneur.61.5.661

• Consumption of Fish and n-3 Fatty Acids and Risk of Incident Alzheimer Disease

  Archives of Neurology · 2003 · 10.1001/archneur.60.7.940

• Alzheimer Disease in the US Population

  Archives of Neurology · 2003 · 10.1001/archneur.60.8.1119

• Natural history of mild cognitive impairment in older persons

  Neurology · 2002 · 10.1212/wnl.59.2.198

• An Inventory to Assess Activities of Daily Living for Clinical Trials in Alzheimerʼs Disease

  Alzheimer Disease & Associated Disorders · 1997 · 10.1097/00002093-199700112-00005

• Vascular dementia

  Neurology · 1993 · https://doi.org/10.1212/wnl.43.2.250

Current projects

No projects listed.