Joseph H. Nadeau

Research interests

Publications

• From Peas to Disease: Modifier Genes, Network Resilience, and the Genetics of Health

  The American Journal of Human Genetics · 2017 · https://doi.org/10.1016/j.ajhg.2017.06.004

• IL-33 activates tumor stroma to promote intestinal polyposis

  Proceedings of the National Academy of Sciences · 2015 · https://doi.org/10.1073/pnas.1422445112

• Isolation of Epiblast Stem Cells from Preimplantation Mouse Embryos

  Cell stem cell · 2011 · https://doi.org/10.1016/j.stem.2011.01.016

• Systems medicine and integrated care to combat chronic noncommunicable diseases

  Genome Medicine · 2011 · https://doi.org/10.1186/gm259

• Missing heritability and strategies for finding the underlying causes of complex disease

  Nature Reviews Genetics · 2010 · https://doi.org/10.1038/nrg2809

• Diet-induced hepatocellular carcinoma in genetically predisposed mice

  Human Molecular Genetics · 2009 · https://doi.org/10.1093/hmg/ddp236

• Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

  Proceedings of the National Academy of Sciences · 2008 · https://doi.org/10.1073/pnas.0810388105

• The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours

  Nature · 2005 · https://doi.org/10.1038/nature03595

• The Collaborative Cross, a community resource for the genetic analysis of complex traits

  Nature Genetics · 2004 · https://doi.org/10.1038/ng1104-1133

• Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

  Science · 2004 · https://doi.org/10.1126/science.1093139

• Finding Genes That Underlie Complex Traits

  Science · 2002 · https://doi.org/10.1126/science.1076641

• Modifier genes in mice and humans

  Nature Reviews Genetics · 2001 · https://doi.org/10.1038/35056009

• Analysing complex genetic traits with chromosome substitution strains

  Nature Genetics · 2000 · https://doi.org/10.1038/73427

• The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs

  Nature Genetics · 2000 · https://doi.org/10.1038/78051

• Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene

  Developmental Dynamics · 1999 · https://doi.org/10.1002/(sici)1097-0177(199909)216:1<72::aid-dvdy9>3.0.co;2-9

• Genealogy of the 129 inbred strains: 129/SvJ is a contaminated inbred strain

  Mammalian Genome · 1997 · https://doi.org/10.1007/s003359900453

• Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus

  Nature Genetics · 1997 · https://doi.org/10.1038/ng0397-289

• Comparable Rates of Gene Loss and Functional Divergence After Genome Duplications Early in Vertebrate Evolution

  Genetics · 1997 · https://doi.org/10.1093/genetics/147.3.1259

• Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

  Nature Genetics · 1996 · https://doi.org/10.1038/ng0396-280

• Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

  Mammalian Genome · 1994 · https://doi.org/10.1007/bf00389540

• A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects

  Science · 1993 · https://doi.org/10.1126/science.8211130

• Cloning and Functional Characterization of a Family of Receptors for the Melanotropic Peptides

  Annals of the New York Academy of Sciences · 1993 · https://doi.org/10.1111/j.1749-6632.1993.tb19694.x

• Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos

  Development · 1992 · https://doi.org/10.1242/dev.116.4.1123

• Maps of linkage and synteny homologies between mouse and man

  Trends in Genetics · 1989 · https://doi.org/10.1016/0168-9525(89)90031-0

• Lengths of chromosomal segments conserved since divergence of man and mouse.

  Proceedings of the National Academy of Sciences · 1984 · https://doi.org/10.1073/pnas.81.3.814

Current projects

No projects listed.