Calman A. MacLennan

Research interests

Publications

• The Shigella Vaccines Pipeline

  Vaccines · 2022 · 10.3390/vaccines10091376

• Outer membrane vesicle vaccines

  Seminars in Immunology · 2020 · https://doi.org/10.1016/j.smim.2020.101433

• Invasive Nontyphoidal Salmonella Disease in Africa

  EcoSal Plus · 2019 · 10.1128/ecosalplus.esp-0007-2018

• Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal Salmonella

  Proceedings of the National Academy of Sciences · 2018 · 10.1073/pnas.1807655115

• Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990–2016

  The Lancet Infectious Diseases · 2018 · https://doi.org/10.1016/s1473-3099(18)30475-4

• A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014)

  PLoS neglected tropical diseases · 2017 · https://doi.org/10.1371/journal.pntd.0005118

• Cytokine Profiles in Malawian Children Presenting with Uncomplicated Malaria, Severe Malarial Anemia, and Cerebral Malaria

  Clinical and Vaccine Immunology · 2017 · 10.1128/cvi.00533-16

• Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3644

• An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12827

• Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3281

• An O Antigen Capsule Modulates Bacterial Pathogenesis in Shigella sonnei

  PLoS Pathogens · 2015 · 10.1371/journal.ppat.1004749

• Vaccines against invasiveSalmonelladisease

  Human Vaccines & Immunotherapeutics · 2014 · https://doi.org/10.4161/hv.29054

• Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2423

• Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.0910497107

• Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults

  Science · 2010 · https://doi.org/10.1126/science.1180346

• Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

  Genome Research · 2009 · https://doi.org/10.1101/gr.091017.109

• The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children

  Journal of Clinical Investigation · 2008 · https://doi.org/10.1172/jci33998

• Interleukin (IL)–12 and IL‐23 Are Key Cytokines for Immunity against Salmonella in Humans

  The Journal of Infectious Diseases · 2004 · https://doi.org/10.1086/425021

• Failure to clear persistent vaccine-derived neurovirulent poliovirus infection in an immunodeficient man

  The Lancet · 2004 · https://doi.org/10.1016/s0140-6736(04)16150-3

Current projects

No projects listed.