Róbert Langer

Research interests

Publications

• A translational framework to DELIVER nanomedicines to the clinic

  Nature Nanotechnology · 2024 · https://doi.org/10.1038/s41565-024-01754-7

• Hydrogels for RNA delivery

  Nature Materials · 2023 · https://doi.org/10.1038/s41563-023-01472-w

• Targeting angiogenesis in oncology, ophthalmology and beyond

  Nature Reviews Drug Discovery · 2023 · https://doi.org/10.1038/s41573-023-00671-z

• The landscape of mRNA nanomedicine

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-02061-1

• Bioplastics for a circular economy

  Nature Reviews Materials · 2022 · 10.1038/s41578-021-00407-8

• Lipid nanoparticles for mRNA delivery

  Nature Reviews Materials · 2021 · https://doi.org/10.1038/s41578-021-00358-0

• Advances in oligonucleotide drug delivery

  Nature Reviews Drug Discovery · 2020 · https://doi.org/10.1038/s41573-020-0075-7

• Engineering precision nanoparticles for drug delivery

  Nature Reviews Drug Discovery · 2020 · https://doi.org/10.1038/s41573-020-0090-8

• Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

  Nature Biomedical Engineering · 2020 · https://doi.org/10.1038/s41551-019-0508-y

• A materials-science perspective on tackling COVID-19

  Nature Reviews Materials · 2020 · https://doi.org/10.1038/s41578-020-00247-y

• Delivery technologies for cancer immunotherapy

  Nature Reviews Drug Discovery · 2019 · https://doi.org/10.1038/s41573-018-0006-z

• Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents

  Advanced Materials · 2018 · https://doi.org/10.1002/adma.201706356

• In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis

  Nature Biotechnology · 2017 · https://doi.org/10.1038/nbt.3836

• Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

  Proceedings of the National Academy of Sciences · 2016 · https://doi.org/10.1073/pnas.1606050113

• Physical and mechanical properties of PLA, and their functions in widespread applications — A comprehensive review

  Advanced Drug Delivery Reviews · 2016 · 10.1016/j.addr.2016.06.012

• Supramolecular biomaterials

  Nature Materials · 2015 · 10.1038/nmat4474

• Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1322937111

• Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

  Nature Nanotechnology · 2012 · https://doi.org/10.1038/nnano.2012.73

• Forty-Year Journey of Angiogenesis Translational Research

  Science Translational Medicine · 2011 · https://doi.org/10.1126/scitranslmed.3003149

• Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0905432106

• Gold, Poly(β-amino ester) Nanoparticles for Small Interfering RNA Delivery

  Nano Letters · 2009 · https://doi.org/10.1021/nl9009793

• Knocking down barriers: advances in siRNA delivery

  Nature Reviews Drug Discovery · 2009 · 10.1038/nrd2742

• A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery

  Accounts of Chemical Research · 2008 · https://doi.org/10.1021/ar7002336

• Transdermal drug delivery

  Nature Biotechnology · 2008 · 10.1038/nbt.1504

• Combinatorial Modification of Degradable Polymers Enables Transfection of Human Cells Comparable to Adenovirus

  Advanced Materials · 2007 · https://doi.org/10.1002/adma.200700371

• Nanocarriers as an emerging platform for cancer therapy

  Nature Nanotechnology · 2007 · https://doi.org/10.1038/nnano.2007.387

• Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology

  Advanced Materials · 2006 · https://doi.org/10.1002/adma.200501612

• Cartilage-like Tissue Engineering Using Silk Scaffolds and Mesenchymal Stem Cells

  Tissue Engineering · 2006 · https://doi.org/10.1089/ten.2006.12.2729

• Biodegradable Polymeric Vectors for Gene Delivery to Human Endothelial Cells

  Bioconjugate Chemistry · 2006 · https://doi.org/10.1021/bc0600968

• Light-induced shape-memory polymers

  Nature · 2005 · 10.1038/nature03496

• Designing materials for biology and medicine

  Nature · 2004 · 10.1038/nature02388

• Polyanhydrides: an overview

  Advanced Drug Delivery Reviews · 2002 · https://doi.org/10.1016/s0169-409x(02)00050-9

• Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications

  Science · 2002 · 10.1126/science.1066102

• Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks

  Journal of Biomedical Materials Research · 2000 · https://doi.org/10.1002/(sici)1097-4636(200008)51:2<164::aid-jbm4>3.0.co;2-w

• Polymeric Systems for Controlled Drug Release

  Chemical Reviews · 1999 · 10.1021/cr940351u

• Transdermal photopolymerization for minimally invasive implantation

  Proceedings of the National Academy of Sciences · 1999 · https://doi.org/10.1073/pnas.96.6.3104

• Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI Trial

  JAMA · 1995 · https://doi.org/10.1001/jama.273.3.199

• The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres

  Advanced Drug Delivery Reviews · 1995 · https://doi.org/10.1016/0169-409x(95)00026-4

• Biodegradable Long-Circulating Polymeric Nanospheres

  Science · 1994 · 10.1126/science.8128245

• Tissue Engineering

  Science · 1993 · https://doi.org/10.1126/science.8493529

• Ultrasound-enhanced polymer degradation and release of incorporated substances.

  Proceedings of the National Academy of Sciences · 1989 · https://doi.org/10.1073/pnas.86.20.7663

• Bioerodible polyanhydrides as drug‐carrier matrices. I: Characterization, degradation, and release characteristics

  Journal of Biomedical Materials Research · 1985 · https://doi.org/10.1002/jbm.820190806

Current projects

No projects listed.