Yu‐Hua Tseng

Research interests

Publications

• Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue

  Cell Metabolism · 2022 · https://doi.org/10.1016/j.cmet.2022.02.016

• β3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis

  JCI Insight · 2021 · 10.1172/jci.insight.139160

• 12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake

  Cell Metabolism · 2018 · 10.1016/j.cmet.2018.03.020

• The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue

  Nature Medicine · 2017 · 10.1038/nm.4297

• Genetic and functional characterization of clonally derived adult human brown adipocytes

  Nature Medicine · 2015 · 10.1038/nm.3819

• A Novel Role for Subcutaneous Adipose Tissue in Exercise-Induced Improvements in Glucose Homeostasis

  Diabetes · 2015 · 10.2337/db14-0704

• Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes

  Nature Medicine · 2015 · 10.1038/nm.3881

• Brown fat fuel utilization and thermogenesis

  Trends in Endocrinology and Metabolism · 2014 · 10.1016/j.tem.2013.12.004

• IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α

  Cell · 2014 · 10.1016/j.cell.2014.04.049

• Lung Stem Cell Differentiation in Mice Directed by Endothelial Cells via a BMP4-NFATc1-Thrombospondin-1 Axis

  Cell · 2014 · 10.1016/j.cell.2013.12.039

• Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

  Nature Medicine · 2013 · 10.1038/nm.3112

• Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat

  Nature · 2013 · 10.1038/nature11943

• Intrinsic Differences in Adipocyte Precursor Cells From Different White Fat Depots

  Diabetes · 2012 · 10.2337/db11-1753

• Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

  Journal of Clinical Investigation · 2012 · https://doi.org/10.1172/jci62308

• Cellular bioenergetics as a target for obesity therapy

  Nature Reviews Drug Discovery · 2010 · 10.1038/nrd3138

• Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1010929108

• Identification and Importance of Brown Adipose Tissue in Adult Humans

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0810780

• New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

  Nature · 2008 · 10.1038/nature07221

• Dissection of the insulin signaling pathway via quantitative phosphoproteomics

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0711713105

• Developmental Origin of Fat: Tracking Obesity to Its Source

  Cell · 2007 · https://doi.org/10.1016/j.cell.2007.10.004

• Loss of ARNT/HIF1β Mediates Altered Gene Expression and Pancreatic-Islet Dysfunction in Human Type 2 Diabetes

  Cell · 2005 · 10.1016/j.cell.2005.05.027

• Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse

  Proceedings of the National Academy of Sciences · 2004 · https://doi.org/10.1073/pnas.0402511101

• Molecular Balance between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival

  Molecular and Cellular Biology · 2002 · https://doi.org/10.1128/mcb.22.3.965-977.2002

Current projects

No projects listed.