Carlos A. Ramos

Research interests

Publications

• Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers

  Nature · 2024 · 10.1038/s41586-024-08261-8

• Preparing for CAR T cell therapy: patient selection, bridging therapies and lymphodepletion

  Nature Reviews Clinical Oncology · 2022 · 10.1038/s41571-022-00607-3

• Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma

  Nature Communications · 2020 · 10.1038/s41467-020-18444-2

• Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma

  Journal of Clinical Oncology · 2020 · 10.1200/jco.20.01342

• Side-effect management of chimeric antigen receptor (CAR) T-cell therapy

  Annals of Oncology · 2020 · https://doi.org/10.1016/j.annonc.2020.10.478

• Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma

  Journal of Clinical Oncology · 2018 · 10.1200/jco.2017.74.3179

• CD7 CAR T Cells for the Therapy of Acute Myeloid Leukemia

  Molecular Therapy · 2018 · 10.1016/j.ymthe.2018.10.001

• In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin’s Lymphomas

  Molecular Therapy · 2018 · 10.1016/j.ymthe.2018.09.009

• Clinical and immunological responses after CD30-specific chimeric antigen receptor–redirected lymphocytes

  Journal of Clinical Investigation · 2017 · 10.1172/jci94306

• Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2017.73.0655

• Clinical responses with T lymphocytes targeting malignancy-associated κ light chains

  Journal of Clinical Investigation · 2016 · 10.1172/jci86000

• Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs

  Blood · 2015 · 10.1182/blood-2015-01-621474

• CAR-T Cell Therapy for Lymphoma

  Annual Review of Medicine · 2015 · 10.1146/annurev-med-051914-021702

• Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

  Blood · 2014 · https://doi.org/10.1182/blood-2014-01-552174

• Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antiviral and Antileukemic Activity

  Clinical Cancer Research · 2014 · 10.1158/1078-0432.ccr-13-3205

• Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

  Blood · 2013 · https://doi.org/10.1182/blood-2013-06-506741

• Sustained Complete Responses in Patients With Lymphoma Receiving Autologous Cytotoxic T Lymphocytes Targeting Epstein-Barr Virus Latent Membrane Proteins

  Journal of Clinical Oncology · 2013 · https://doi.org/10.1200/jco.2013.51.5304

• Chimeric antigen receptor (CAR)-engineered lymphocytes for cancer therapy

  Expert Opinion on Biological Therapy · 2011 · 10.1517/14712598.2011.573476

• FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia

  Journal of Antimicrobial Chemotherapy · 2011 · https://doi.org/10.1093/jac/dkr097

• Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue

  Current Opinion in Hematology · 2006 · https://doi.org/10.1097/01.moh.0000219664.26528.da

• Tie2 activation contributes to hemangiogenic regeneration after myelosuppression

  Blood · 2005 · 10.1182/blood-2004-11-4269

• Human mesenchymal stem cells are tolerized by mice and improve skin and spinal cord injuries

  Transplantation Proceedings · 2005 · 10.1016/j.transproceed.2005.01.070

• Molecular Signatures of Proliferation and Quiescence in Hematopoietic Stem Cells

  PLoS Biology · 2004 · https://doi.org/10.1371/journal.pbio.0020301

• The Nuclear Topography of ABL, BCR, PML, and RAR Genes: Evidence for Gene Proximity in Specific Phases of the Cell Cycle and Stages of Hematopoietic Differentiation

  Blood · 1999 · 10.1182/blood.v93.4.1197

• Spatial Organization of Large-Scale Chromatin Domains in the Nucleus: A Magnified View of Single Chromosome Territories

  The Journal of Cell Biology · 1997 · 10.1083/jcb.139.7.1597

Current projects

No projects listed.