Tilman Grune

Research interests

Publications

• Sarcopenia – Molecular mechanisms and open questions

  Ageing Research Reviews · 2020 · https://doi.org/10.1016/j.arr.2020.101200

• Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

  Archives of Toxicology · 2020 · https://doi.org/10.1007/s00204-020-02725-2

• Proteostasis, oxidative stress and aging

  Redox Biology · 2017 · https://doi.org/10.1016/j.redox.2017.07.008

• Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

  Redox Biology · 2016 · https://doi.org/10.1016/j.redox.2016.12.001

• Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

  Redox Biology · 2015 · https://doi.org/10.1016/j.redox.2015.06.005

• Clinical Relevance of Biomarkers of Oxidative Stress

  Antioxidants and Redox Signaling · 2015 · https://doi.org/10.1089/ars.2015.6317

• Advanced Glycation End Products and Oxidative Stress in Type 2 Diabetes Mellitus

  Biomolecules · 2015 · https://doi.org/10.3390/biom5010194

• Role of advanced glycation end products in cellular signaling

  Redox Biology · 2014 · https://doi.org/10.1016/j.redox.2013.12.016

• Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products

  Free Radical Research · 2013 · https://doi.org/10.3109/10715762.2013.792926

• Lipofuscin: formation, effects and role of macroautophagy

  Redox Biology · 2013 · https://doi.org/10.1016/j.redox.2013.01.006

• β-Carotene Is an Important Vitamin A Source for Humans

  Journal of Nutrition · 2010 · https://doi.org/10.3945/jn.109.119024

• Pathological aspects of lipid peroxidation

  Free Radical Research · 2010 · https://doi.org/10.3109/10715762.2010.498478

• The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes

  Biochemical Journal · 2010 · https://doi.org/10.1042/bj20100878

• The proteasomal system

  Molecular Aspects of Medicine · 2009 · https://doi.org/10.1016/j.mam.2009.04.001

• Lipofuscin

  Annals of the New York Academy of Sciences · 2007 · https://doi.org/10.1196/annals.1404.008

• Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and ‘aggresomes’ during oxidative stress, aging, and disease

  The International Journal of Biochemistry & Cell Biology · 2004 · https://doi.org/10.1016/j.biocel.2004.04.020

• Proteasome inhibition by paired helical filament‐tau in brains of patients with Alzheimer's disease

  Journal of Neurochemistry · 2003 · https://doi.org/10.1046/j.1471-4159.2003.01642.x

• Selective degradation of oxidatively modified protein substrates by the proteasome

  Biochemical and Biophysical Research Communications · 2003 · https://doi.org/10.1016/s0006-291x(03)00809-x

• Ubiquitin Conjugation Is Not Required for the Degradation of Oxidized Proteins by Proteasome

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m206279200

• Comparative resistance of the 20S and 26S proteasome to oxidative stress

  Biochemical Journal · 1998 · https://doi.org/10.1042/bj3350637

• Degradation of oxidized proteins in mammalian cells

  The FASEB Journal · 1997 · https://doi.org/10.1096/fasebj.11.7.9212076

• Degradation of Oxidized Proteins in K562 Human Hematopoietic Cells by Proteasome

  Journal of Biological Chemistry · 1996 · https://doi.org/10.1074/jbc.271.26.15504

• Proteolysis in Cultured Liver Epithelial Cells during Oxidative Stress

  Journal of Biological Chemistry · 1995 · https://doi.org/10.1074/jbc.270.5.2344

Current projects

No projects listed.