Joshua Zimmerberg

Research interests

Publications

• Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

  Science · 2017 · https://doi.org/10.1126/science.aan1478

• A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells

  Stem Cell Reports · 2014 · https://doi.org/10.1016/j.stemcr.2014.11.002

• Lipid Polymorphisms and Membrane Shape

  Cold Spring Harbor Perspectives in Biology · 2011 · https://doi.org/10.1101/cshperspect.a004747

• GTPase Cycle of Dynamin Is Coupled to Membrane Squeeze and Release, Leading to Spontaneous Fission

  Cell · 2008 · 10.1016/j.cell.2008.11.028

• Progressive ordering with decreasing temperature of the phospholipids of influenza virus

  Nature Chemical Biology · 2008 · 10.1038/nchembio.77

• Dynamic clustered distribution of hemagglutinin resolved at 40 nm in living cell membranes discriminates between raft theories

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0708066104

• Membranes of the world unite!

  The Journal of Cell Biology · 2006 · https://doi.org/10.1083/jcb.200607083

• How proteins produce cellular membrane curvature

  Nature Reviews Molecular Cell Biology · 2005 · https://doi.org/10.1038/nrm1784

• Dynamics of putative raft-associated proteins at the cell surface

  The Journal of Cell Biology · 2004 · 10.1083/jcb.200312170

• Line Tension and Interaction Energies of Membrane Rafts Calculated from Lipid Splay and Tilt

  Biophysical Journal · 2004 · 10.1529/biophysj.104.048223

• Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature

  Journal of Biological Chemistry · 2002 · 10.1074/jbc.m206069200

• Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3

  Nature Cell Biology · 2001 · 10.1038/35055095

• A quantitative model for membrane fusion based on low-energy intermediates

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.121191898

• Implications of lipid microdomains for membrane curvature, budding and fission

  Current Opinion in Cell Biology · 2001 · 10.1016/s0955-0674(00)00239-8

• A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite

  Nature · 2000 · 10.1038/35023000

• Bax, but not Bcl-x L , decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations

  Proceedings of the National Academy of Sciences · 1999 · 10.1073/pnas.96.10.5492

• The Pathway of Membrane Fusion Catalyzed by Influenza Hemagglutinin: Restriction of Lipids, Hemifusion, and Lipidic Fusion Pore Formation

  The Journal of Cell Biology · 1998 · 10.1083/jcb.140.6.1369

• An Early Stage of Membrane Fusion Mediated by the Low pH Conformation of Influenza Hemagglutinin Depends upon Membrane Lipids

  The Journal of Cell Biology · 1997 · https://doi.org/10.1083/jcb.136.1.81

• Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore.

  Proceedings of the National Academy of Sciences · 1996 · 10.1073/pnas.93.16.8413

• The hemifusion intermediate and its conversion to complete fusion: regulation by membrane composition

  Biophysical Journal · 1995 · 10.1016/s0006-3495(95)79966-0

• Lipids in biological membrane fusion

  The Journal of Membrane Biology · 1995 · 10.1007/bf00232676

• Membrane dipole potentials, hydration forces, and the ordering of water at membrane surfaces

  Biophysical Journal · 1992 · 10.1016/s0006-3495(92)81931-8

• Simultaneous electrical and optical measurements show that membrane fusion precedes secretory granule swelling during exocytosis of beige mouse mast cells.

  Proceedings of the National Academy of Sciences · 1987 · 10.1073/pnas.84.6.1585

• Polymer inaccessible volume changes during opening and closing of a voltage-dependent ionic channel

  Nature · 1986 · 10.1038/323036a0

• Fusion of phospholipid vesicles with planar phospholipid bilayer membranes. II. Incorporation of a vesicular membrane marker into the planar membrane.

  The Journal of General Physiology · 1980 · https://doi.org/10.1085/jgp.75.3.251

Current projects

No projects listed.