Dena Hernández

Research interests

Publications

• Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study

  The Lancet Neurology · 2023 · https://doi.org/10.1016/s1474-4422(23)00283-1

• Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets

  JAMA Neurology · 2021 · https://doi.org/10.1001/jamaneurol.2020.5257

• Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-26280-1

• Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00785-3

• Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30320-5

• Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

  The Lancet Neurology · 2017 · https://doi.org/10.1016/s1474-4422(17)30400-3

• DNA methylation-based measures of biological age: meta-analysis predicting time to death

  Aging · 2016 · https://doi.org/10.18632/aging.101020

• A DNA methylation biomarker of alcohol consumption

  Molecular Psychiatry · 2016 · https://doi.org/10.1038/mp.2016.192

• Epigenetic Signatures of Cigarette Smoking

  Circulation Cardiovascular Genetics · 2016 · https://doi.org/10.1161/circgenetics.116.001506

• New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms10495

• The transcriptional landscape of age in human peripheral blood

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms9570

• A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2608

• A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.668

• Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

  Neuron · 2010 · 10.1016/j.neuron.2010.11.036

• Common variants at 19p13 are associated with susceptibility to ovarian cancer

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.666

• Genome-wide association study reveals genetic risk underlying Parkinson's disease

  Nature Genetics · 2009 · 10.1038/ng.487

• Characterization of PLA2G6 as a locus for dystonia‐parkinsonism

  Annals of Neurology · 2008 · https://doi.org/10.1002/ana.21415

• Deletion at ITPR1 Underlies Ataxia in Mice and Spinocerebellar Ataxia 15 in Humans

  PLoS Genetics · 2007 · https://doi.org/10.1371/journal.pgen.0030108

• Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11

  Nature Genetics · 2007 · https://doi.org/10.1038/ng.2007.43

Current projects

No projects listed.