Carlos A. Aguilar‐Salinas

Research interests

Publications

• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

  Nature · 2024 · https://doi.org/10.1038/s41586-024-07019-6

• Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

  The Lancet · 2024 · https://doi.org/10.1016/s0140-6736(23)02750-2

• A genomic mutational constraint map using variation in 76,156 human genomes

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06045-0

• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01058-3

• Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

  The Lancet · 2021 · 10.1016/s0140-6736(21)01330-1

• Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus statement from the European Atherosclerosis Society

  European Heart Journal · 2021 · https://doi.org/10.1093/eurheartj/ehab551

• Predicting Mortality Due to SARS-CoV-2: A Mechanistic Score Relating Obesity and Diabetes to COVID-19 Outcomes in Mexico

  The Journal of Clinical Endocrinology & Metabolism · 2020 · 10.1210/clinem/dgaa346

• The mutational constraint spectrum quantified from variation in 141,456 humans

  Nature · 2020 · 10.1038/s41586-020-2308-7

• A structural variation reference for medical and population genetics

  Nature · 2020 · 10.1038/s41586-020-2287-8

• Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia

  JAMA Cardiology · 2020 · 10.1001/jamacardio.2019.5173

• METS-IR, a novel score to evaluate insulin sensitivity, is predictive of visceral adiposity and incident type 2 diabetes

  European Journal of Endocrinology · 2018 · 10.1530/eje-17-0883

• Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

  Atherosclerosis · 2018 · 10.1016/j.atherosclerosis.2018.08.051

• Transancestral mapping and genetic load in systemic lupus erythematosus

  Nature Communications · 2017 · 10.1038/ncomms16021

• The Lancet Commission on pollution and health

  The Lancet · 2017 · 10.1016/s0140-6736(17)32345-0

• Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

  The Lancet · 2016 · 10.1016/s0140-6736(16)31919-5

• A novel risk score to predict cardiovascular disease risk in national populations (Globorisk): a pooled analysis of prospective cohorts and health examination surveys

  The Lancet Diabetes & Endocrinology · 2015 · 10.1016/s2213-8587(15)00081-9

• Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population

  JAMA · 2014 · 10.1001/jama.2014.6511

• Reconstructing Native American population history

  Nature · 2012 · 10.1038/nature11258

• TSH and free thyroxine concentrations are associated with differing metabolic markers in euthyroid subjects

  European Journal of Endocrinology · 2010 · 10.1530/eje-10-0312

• Metabolic syndrome and non-alcoholic fatty liver disease

  Annals of Hepatology · 2009 · 10.1016/s1665-2681(19)31822-8

• Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetes

  Current Medical Research and Opinion · 2009 · 10.1185/03007990903178735

• Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides

  Nature Genetics · 2008 · 10.1038/ng.2007.61

• High Adiponectin Concentrations Are Associated with the Metabolically Healthy Obese Phenotype

  The Journal of Clinical Endocrinology & Metabolism · 2008 · 10.1210/jc.2007-2724

• A Genomewide Admixture Map for Latino Populations

  The American Journal of Human Genetics · 2007 · 10.1086/518313

• High prevalence of low HDL cholesterol concentrations and mixed hyperlipidemia in a Mexican nationwide survey

  Journal of Lipid Research · 2001 · 10.1016/s0022-2275(20)31581-9

Current projects

No projects listed.