Curtis C. Harris

Research interests

Publications

• Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-03224-w

• Interaction between the microbiome and TP53 in human lung cancer

  Genome biology · 2018 · https://doi.org/10.1186/s13059-018-1501-6

• Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer

  Cell Reports · 2017 · https://doi.org/10.1016/j.celrep.2017.08.041

• Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease−Associated Colorectal Cancers

  Gastroenterology · 2016 · https://doi.org/10.1053/j.gastro.2015.12.036

• Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms11843

• An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers

  Journal of Thoracic Oncology · 2015 · https://doi.org/10.1097/jto.0000000000000560

• Fusobacterium nucleatum and T Cells in Colorectal Carcinoma

  JAMA Oncology · 2015 · https://doi.org/10.1001/jamaoncol.2015.1377

• A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2608

• KIF5B-RET fusions in lung adenocarcinoma

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2644

• Detectable clonal mosaicism and its relationship to aging and cancer

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2270

• Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

  Oncogene · 2012 · https://doi.org/10.1038/onc.2012.288

• Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium

  European Journal of Cancer · 2012 · https://doi.org/10.1016/j.ejca.2012.01.038

• Circulating Plasma MiR-141 Is a Novel Biomarker for Metastatic Colon Cancer and Predicts Poor Prognosis

  PLoS ONE · 2011 · https://doi.org/10.1371/journal.pone.0017745

• Genetic variation in microRNA networks: the implications for cancer research

  Nature reviews. Cancer · 2010 · https://doi.org/10.1038/nrc2867

• Microenvironmental modulation of asymmetric cell division in human lung cancer cells

  Proceedings of the National Academy of Sciences · 2010 · https://doi.org/10.1073/pnas.0909390107

• Clinical Outcomes and Correlates of TP53 Mutations and Cancer

  Cold Spring Harbor Perspectives in Biology · 2009 · https://doi.org/10.1101/cshperspect.a001016

• MicroRNA Expression Profiles Associated With Prognosis and Therapeutic Outcome in Colon Adenocarcinoma

  JAMA · 2008 · https://doi.org/10.1001/jama.299.4.425

• Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

  The Journal of Cell Biology · 2004 · https://doi.org/10.1083/jcb.200405128

• p53-Induced Up-Regulation of MnSOD and GPx but not Catalase Increases Oxidative Stress and Apoptosis

  Cancer Research · 2004 · https://doi.org/10.1158/0008-5472.can-2287-2

• The p53 network in lung carcinogenesis

  Oncogene · 2002 · https://doi.org/10.1038/sj.onc.1205563

• Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles.

  PubMed · 2002

• Functional Interaction of p53 and BLM DNA Helicase in Apoptosis

  Journal of Biological Chemistry · 2001 · https://doi.org/10.1074/jbc.m103298200

• APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis.

  PubMed · 2001

• p53-Mediated apoptosis is attenuated in Werner syndrome cells

  Genes & Development · 1999 · https://doi.org/10.1101/gad.13.11.1355

Current projects

No projects listed.