Sridhar Hannenhalli

Research interests

Publications

• Big data in basic and translational cancer research

  Nature reviews. Cancer · 2022 · 10.1038/s41568-022-00502-0

• Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

  Cell · 2021 · 10.1016/j.cell.2021.02.048

• Synthetic lethality-mediated precision oncology via the tumor transcriptome

  Cell · 2021 · 10.1016/j.cell.2021.03.030

• Harnessing synthetic lethality to predict the response to cancer treatment

  Nature Communications · 2018 · 10.1038/s41467-018-04647-1

• Analysis and correction of compositional bias in sparse sequencing count data

  BMC Genomics · 2018 · 10.1186/s12864-018-5160-5

• Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

  Cell · 2018 · 10.1016/j.cell.2018.07.019

• RNA-Seq identifies novel myocardial gene expression signatures of heart failure

  Genomics · 2014 · 10.1016/j.ygeno.2014.12.002

• Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus

  Physiological Genomics · 2012 · 10.1152/physiolgenomics.00084.2012

• Why Transcription Factor Binding Sites Are Ten Nucleotides Long

  Genetics · 2012 · 10.1534/genetics.112.143370

• Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte Proliferation

  Developmental Cell · 2010 · 10.1016/j.devcel.2010.08.012

• The evolution of Fox genes and their role in development and disease

  Nature Reviews Genetics · 2009 · https://doi.org/10.1038/nrg2523

• Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

  Development · 2008 · 10.1242/dev.024539

• Selection of Target Sites for Mobile DNA Integration in the Human Genome

  PLoS Computational Biology · 2006 · 10.1371/journal.pcbi.0020157

• Transcriptional Genomics Associates FOX Transcription Factors With Human Heart Failure

  Circulation · 2006 · 10.1161/circulationaha.106.632430

• Retroviral DNA Integration: Viral and Cellular Determinants of Target-Site Selection

  PLoS Pathogens · 2006 · 10.1371/journal.ppat.0020060

• Genome-wide analysis of retroviral DNA integration

  Nature Reviews Microbiology · 2005 · 10.1038/nrmicro1263

• Genome-Wide Analysis of Chromosomal Features Repressing Human Immunodeficiency Virus Transcription

  Journal of Virology · 2005 · 10.1128/jvi.79.11.6610-6619.2005

• Whole-genome shotgun assembly and comparison of human genome assemblies

  Proceedings of the National Academy of Sciences · 2004 · 10.1073/pnas.0307971100

• 1.375-Approximation Algorithm for Sorting by Reversals

  Lecture notes in computer science · 2002 · https://doi.org/10.1007/3-540-45749-6_21

• Transforming men into mice (polynomial algorithm for genomic distance problem)

  · 2002 · 10.1109/sfcs.1995.492588

• The Sequence of the Human Genome

  Science · 2001 · https://doi.org/10.1126/science.1058040

• Analysis and prediction of functional sub-types from protein sequence alignments

  Journal of Molecular Biology · 2000 · 10.1006/jmbi.2000.4036

• Transforming cabbage into turnip

  Journal of the ACM · 1999 · https://doi.org/10.1145/300515.300516

• Polynomial-time algorithm for computing translocation distance between genomes

  Discrete Applied Mathematics · 1996 · 10.1016/s0166-218x(96)00061-3

Current projects

No projects listed.