Barry J. Hoffer

Research interests

Publications

• Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

  Nature · 2013 · https://doi.org/10.1038/nature12474

• High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio

  Proceedings of the National Academy of Sciences · 2010 · https://doi.org/10.1073/pnas.1008189107

• GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0806720106

• Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

  Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0605208103

• Characterization of a mouse strain expressing Cre recombinase from the 3′ untranslated region of the dopamine transporter locus

  genesis · 2006 · https://doi.org/10.1002/dvg.20228

• Dopamine Neuron Agenesis in Nurr1-Deficient Mice

  Science · 1997 · https://doi.org/10.1126/science.276.5310.248

• Defects in enteric innervation and kidney development in mice lacking GDNF

  Nature · 1996 · https://doi.org/10.1038/382073a0

• Glial cell line‐derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons

  The Journal of Comparative Neurology · 1995 · https://doi.org/10.1002/cne.903550402

• Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

  Nature · 1995 · https://doi.org/10.1038/373335a0

• Glial Cell Line-Derived Neurotrophic Factor Is Expressed in the Developing but Not Adult Striatum and Stimulates Developing Dopamine Neurons in Vivo

  Experimental Neurology · 1993 · https://doi.org/10.1006/exnr.1993.1214

• Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats

  Brain Research · 1993 · https://doi.org/10.1016/0006-8993(93)90576-9

• Blood-Brain Barrier Penetration and in Vivo Activity of an NGF Conjugate

  Science · 1993 · https://doi.org/10.1126/science.8420006

• Transplantation in Parkinson's disease: Two cases of adrenal medullary grafts to the putamen

  Annals of Neurology · 1987 · https://doi.org/10.1002/ana.410220403

• Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour

  Nature · 1981 · https://doi.org/10.1038/292351a0

• ADENINE NUCLEOTIDES AND SYNAPTIC TRANSMISSION IN THE in vitro RAT HIPPOCAMPUS

  British Journal of Pharmacology · 1980 · https://doi.org/10.1111/j.1476-5381.1980.tb10883.x

• Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long‐term behavioral, biochemical, and histochemical studies

  Annals of Neurology · 1980 · https://doi.org/10.1002/ana.410080508

• Brain Grafts Reduce Motor Abnormalities Produced by Destruction of Nigrostriatal Dopamine System

  Science · 1979 · https://doi.org/10.1126/science.571147

• Activation of the pathway from locus coeruleus to rat cerebellar Purkinje neurons: pharmacological evidence of noradrenergic central inhibition.

  PubMed · 1973

• The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells

  Brain Research · 1971 · https://doi.org/10.1016/0006-8993(71)90352-0

• Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. I. Localization of the fibers and their synapses

  Brain Research · 1971 · https://doi.org/10.1016/0006-8993(71)90457-4

• Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. II. Sensitivity of Purkinje cells to norepinephrine and related substances administered by microiontophoresis

  Brain Research · 1971 · https://doi.org/10.1016/0006-8993(71)90458-6

• CYCLIC AMP MEDIATION OF NOREPINEPHRINE INHIBITION IN RAT CEREBELLAR CORTEX: A UNIQUE CLASS OF SYNAPTIC RESPONSES

  Annals of the New York Academy of Sciences · 1971 · https://doi.org/10.1111/j.1749-6632.1971.tb45279.x

• Cyclic Adenosine Monophosphate and Norepinephrine: Effects on Transmembrane Properties of Cerebellar Purkinje Cells

  Science · 1971 · https://doi.org/10.1126/science.171.3967.192

• Activation of a Central Noradrenergic Projection to Cerebellum

  Nature · 1971 · https://doi.org/10.1038/233481a0

Current projects

No projects listed.