Carlos A. Zarate

Research interests

Publications

• Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation

  American Journal of Psychiatry · 2021 · https://doi.org/10.1176/appi.ajp.2020.20081251

• ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing

  Translational Psychiatry · 2020 · https://doi.org/10.1038/s41398-020-0842-6

• What is the optimal serum level for lithium in the maintenance treatment of bipolar disorder? A systematic review and recommendations from the ISBD/IGSLI Task Force on treatment with lithium

  Bipolar Disorders · 2019 · https://doi.org/10.1111/bdi.12805

• Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms

  Pharmacological Reviews · 2018 · https://doi.org/10.1124/pr.117.015198

• The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

  American Journal of Psychiatry · 2017 · https://doi.org/10.1176/appi.ajp.2017.17040472

• Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

  Molecular Psychiatry · 2017 · https://doi.org/10.1038/mp.2017.73

• NMDAR inhibition-independent antidepressant actions of ketamine metabolites

  Nature · 2016 · https://doi.org/10.1038/nature17998

• The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

  American Journal of Psychiatry · 2013 · https://doi.org/10.1176/appi.ajp.2013.13020185

• Replication of Ketamine's Antidepressant Efficacy in Bipolar Depression: A Randomized Controlled Add-On Trial

  Biological Psychiatry · 2012 · https://doi.org/10.1016/j.biopsych.2011.12.010

• A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression

  Archives of General Psychiatry · 2010 · https://doi.org/10.1001/archgenpsychiatry.2010.90

• Rapid Resolution of Suicidal Ideation After a Single Infusion of an N -Methyl- D -Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder

  The Journal of Clinical Psychiatry · 2010 · https://doi.org/10.4088/jcp.09m05327blu

• Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

  Nature Reviews Drug Discovery · 2008 · https://doi.org/10.1038/nrd2462

• Cellular Mechanisms Underlying the Antidepressant Effects of Ketamine: Role of α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid Receptors

  Biological Psychiatry · 2007 · https://doi.org/10.1016/j.biopsych.2007.05.028

• A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression

  Archives of General Psychiatry · 2006 · https://doi.org/10.1001/archpsyc.63.8.856

• Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

  Biological Psychiatry · 2003 · https://doi.org/10.1016/s0006-3223(03)00117-3

Current projects

No projects listed.