Riitta Lahesmaa

Research interests

Publications

• An additive Gaussian process regression model for interpretable non-parametric analysis of longitudinal data

  Nature Communications · 2019 · 10.1038/s41467-019-09785-8

• Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation

  Cell · 2019 · https://doi.org/10.1016/j.cell.2018.11.044

• Analysis of the plasma proteome using iTRAQ and TMT‐based Isobaric labeling

  Mass Spectrometry Reviews · 2017 · https://doi.org/10.1002/mas.21550

• Genome-wide Analysis of STAT3-Mediated Transcription during Early Human Th17 Cell Differentiation

  Cell Reports · 2017 · 10.1016/j.celrep.2017.05.013

• Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility

  Diabetes · 2014 · https://doi.org/10.2337/db13-1775

• Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature

  Antioxidants and Redox Signaling · 2014 · 10.1089/ars.2013.5828

• Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

  Nature Immunology · 2014 · 10.1038/ni.2843

• Genetic and epigenetic stability of human pluripotent stem cells

  Nature Reviews Genetics · 2012 · https://doi.org/10.1038/nrg3271

• Timing of infant feeding in relation to childhood asthma and allergic diseases

  Journal of Allergy and Clinical Immunology · 2012 · 10.1016/j.jaci.2012.10.028

• Copy number variation and selection during reprogramming to pluripotency

  Nature · 2011 · https://doi.org/10.1038/nature09871

• Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells

  Cell stem cell · 2011 · https://doi.org/10.1016/j.stem.2011.01.008

• Genomic views of STAT function in CD4+ T helper cell differentiation

  Nature reviews. Immunology · 2011 · 10.1038/nri2958

• High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

  Nature Biotechnology · 2010 · 10.1038/nbt.1615

• Genome-wide Profiling of Interleukin-4 and STAT6 Transcription Factor Regulation of Human Th2 Cell Programming

  Immunity · 2010 · https://doi.org/10.1016/j.immuni.2010.06.011

• A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments

  BMC Genomics · 2009 · 10.1186/1471-2164-10-618

• Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

  The Journal of Experimental Medicine · 2008 · 10.1084/jem.20081800

• Exosomes with Immune Modulatory Features Are Present in Human Breast Milk

  The Journal of Immunology · 2007 · https://doi.org/10.4049/jimmunol.179.3.1969

• Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells

  Journal of Leukocyte Biology · 2007 · https://doi.org/10.1189/jlb.0307194

• Differential Expression of IFN Regulatory Factor 4 Gene in Human Monocyte-Derived Dendritic Cells and Macrophages

  The Journal of Immunology · 2005 · 10.4049/jimmunol.175.10.6570

• Difference in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells.

  PubMed · 2005

• Gene Expression Signatures of Seven Individual Human Embryonic Stem Cell Lines

  Stem Cells · 2005 · 10.1634/stemcells.2004-0341

• Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets

  Diabetologia · 2005 · 10.1007/s00125-005-1839-7

• Identification and Validation of Endogenous Reference Genes for Expression Profiling of T Helper Cell Differentiation by Quantitative Real-Time RT-PCR

  Analytical Biochemistry · 2001 · https://doi.org/10.1006/abio.2001.5369

• Persistence ofYersinia antigens in peripheral blood cells from patients withYersinia enterocolitica O:3 infection with or without reactive arthritis

  Arthritis & Rheumatism · 1998 · 10.1002/1529-0131(199805)41:5<855::aid-art12>3.0.co;2-j

• IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells

  The Journal of Immunology · 1992 · 10.4049/jimmunol.149.7.2378

Current projects

No projects listed.