Jan O. Korbel
Researcher Next ID · RN-022608
Researcher · Biochemistry, Genetics and Molecular Biology
European Molecular Biology Organization
Heidelberg, Germany
- Works count
- 456
- Citation count
- 120,707
- H-index
- 120
- i10-index
- 247
Research interests
Publications
A draft human pangenome reference
Nature · 2023 · https://doi.org/10.1038/s41586-023-05896-x
High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios
Cell · 2022 · https://doi.org/10.1016/j.cell.2022.08.004
Haplotype-resolved diverse human genomes and integrated analysis of structural variation
Science · 2021 · https://doi.org/10.1126/science.abf7117
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0576-7
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0562-0
Eleven grand challenges in single-cell data science
Genome biology · 2020 · 10.1186/s13059-020-1926-6
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
Cell · 2020 · 10.1016/j.cell.2020.08.001
Patterns of somatic structural variation in human cancer genomes
Nature · 2020 · 10.1038/s41586-019-1913-9
Multi-platform discovery of haplotype-resolved structural variation in human genomes
Nature Communications · 2019 · 10.1038/s41467-018-08148-z
The landscape of genomic alterations across childhood cancers
Nature · 2018 · 10.1038/nature25480
The whole-genome landscape of medulloblastoma subtypes
Nature · 2017 · 10.1038/nature22973
An integrated map of structural variation in 2,504 human genomes
Nature · 2015 · https://doi.org/10.1038/nature15394
Comprehensive genomic profiles of small cell lung cancer
Nature · 2015 · 10.1038/nature14664
A global reference for human genetic variation
Nature · 2015 · https://doi.org/10.1038/nature15393
Toward understanding and exploiting tumor heterogeneity
Nature Medicine · 2015 · 10.1038/nm.3915
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Nature · 2014 · 10.1038/nature13379
Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Cancer Cell · 2014 · 10.1016/j.ccr.2014.02.004
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Nature Genetics · 2013 · 10.1038/ng.2682
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
Cell · 2012 · 10.1016/j.cell.2011.12.013
Dissecting the genomic complexity underlying medulloblastoma
Nature · 2012 · 10.1038/nature11284
DELLY: structural variant discovery by integrated paired-end and split-read analysis
Bioinformatics · 2012 · https://doi.org/10.1093/bioinformatics/bts378
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Nature · 2012 · https://doi.org/10.1038/nature10833
Mapping copy number variation by population-scale genome sequencing
Nature · 2011 · 10.1038/nature09708
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Nature · 2007 · https://doi.org/10.1038/nature05874
Paired-End Mapping Reveals Extensive Structural Variation in the Human Genome
Science · 2007 · 10.1126/science.1149504
Current projects
No projects listed.