Ronald M. Evans

Research interests

Publications

• A framework for advancing our understanding of cancer-associated fibroblasts

  Nature reviews. Cancer · 2020 · https://doi.org/10.1038/s41568-019-0238-1

• Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

  Nature · 2016 · https://doi.org/10.1038/nature19084

• Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

  Nature Medicine · 2015 · https://doi.org/10.1038/nm.3760

• PPARγ signaling and metabolism: the good, the bad and the future

  Nature Medicine · 2013 · 10.1038/nm.3159

• Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

  Nature · 2012 · https://doi.org/10.1038/nature11048

• A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2882

• Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

  Nature · 2011 · 10.1038/nature09798

• PPARs and the complex journey to obesity

  Nature Medicine · 2004 · 10.1038/nm1025

• Nuclear Receptors and Lipid Physiology: Opening the X-Files

  Science · 2001 · 10.1126/science.294.5548.1866

• PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

  Molecular Cell · 1999 · 10.1016/s1097-2765(00)80209-9

• PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

  Cell · 1998 · 10.1016/s0092-8674(00)81575-5

• Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

  Cell · 1998 · 10.1016/s0092-8674(00)81574-3

• Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

  Proceedings of the National Academy of Sciences · 1997 · 10.1073/pnas.94.9.4312

• The RXR heterodimers and orphan receptors

  Cell · 1995 · https://doi.org/10.1016/0092-8674(95)90200-7

• The nuclear receptor superfamily: The second decade

  Cell · 1995 · https://doi.org/10.1016/0092-8674(95)90199-x

• A transcriptional co-repressor that interacts with nuclear hormone receptors

  Nature · 1995 · 10.1038/377454a0

• 15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ

  Cell · 1995 · https://doi.org/10.1016/0092-8674(95)90193-0

• Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

  Nature · 1992 · 10.1038/358771a0

• Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

  Nature · 1992 · 10.1038/355446a0

• 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

  Cell · 1992 · 10.1016/0092-8674(92)90479-v

• Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

  Cell · 1991 · 10.1016/0092-8674(91)90020-y

• Nuclear receptor that identifies a novel retinoic acid response pathway

  Nature · 1990 · 10.1038/345224a0

• The Steroid and Thyroid Hormone Receptor Superfamily

  Science · 1988 · https://doi.org/10.1126/science.3283939

• Identification of a receptor for the morphogen retinoic acid

  Nature · 1987 · 10.1038/330624a0

• Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

  Science · 1987 · 10.1126/science.3037703

• The c-erb-A gene encodes a thyroid hormone receptor

  Nature · 1986 · 10.1038/324641a0

• Primary structure and expression of a functional human glucocorticoid receptor cDNA

  Nature · 1985 · 10.1038/318635a0

• Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

  Nature · 1983 · 10.1038/304129a0

• Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

  Nature · 1982 · 10.1038/298240a0

Current projects

No projects listed.