Joseph S. Beckman

Research interests

Publications

• Nitric Oxide and Peroxynitrite in Health and Disease

  Physiological Reviews · 2007 · https://doi.org/10.1152/physrev.00029.2006

• Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

  Proceedings of the National Academy of Sciences · 2006 · 10.1073/pnas.0601945103

• Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?

  Journal of Clinical Investigation · 2003 · 10.1172/jci200317638

• Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?

  Journal of Clinical Investigation · 2003 · 10.1172/jci17638

• Superoxide Reacts with Nitric Oxide to Nitrate Tyrosine at Physiological pH via Peroxynitrite

  Journal of Biological Chemistry · 2000 · 10.1074/jbc.m910433199

• Induction of Nitric Oxide -- Dependent Apoptosis in Motor Neurons by Zinc-Deficient Superoxide Dismutase

  Science · 1999 · 10.1126/science.286.5449.2498

• Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

  Journal of Neuroscience · 1997 · 10.1523/jneurosci.17-08-02653.1997

• Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts.

  Proceedings of the National Academy of Sciences · 1996 · 10.1073/pnas.93.21.11853

• Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

  American Journal of Physiology-Cell Physiology · 1996 · https://doi.org/10.1152/ajpcell.1996.271.5.c1424

• Oxidative Damage and Tyrosine Nitration from Peroxynitrite

  Chemical Research in Toxicology · 1996 · 10.1021/tx9501445

• Evidence for In Vivo Peroxynitrite Production in Human Acute Lung Injury

  American Journal of Respiratory and Critical Care Medicine · 1995 · 10.1164/ajrccm/151.4.1250

• Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

  Journal of Clinical Investigation · 1994 · 10.1172/jci117607

• [23] Oxidative chemistry of peroxynitrite

  Methods in enzymology on CD-ROM/Methods in enzymology · 1994 · 10.1016/s0076-6879(94)33026-3

• ALS, SOD and peroxynitrite

  Nature · 1993 · 10.1038/364584a0

• Pathological implications of nitric oxide, superoxide and peroxynitrite formation

  Biochemical Society Transactions · 1993 · 10.1042/bst0210330

• Peroxynitrite-induced luminol chemiluminescence

  Biochemical Journal · 1993 · 10.1042/bj2900051

• Bactericidal activity of peroxynitrite

  Archives of Biochemistry and Biophysics · 1992 · 10.1016/0003-9861(92)90434-x

• Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

  Archives of Biochemistry and Biophysics · 1992 · https://doi.org/10.1016/0003-9861(92)90431-u

• Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

  Archives of Biochemistry and Biophysics · 1992 · 10.1016/0003-9861(92)90432-v

• Peroxynitrite formation from macrophage-derived nitric oxide

  Archives of Biochemistry and Biophysics · 1992 · 10.1016/0003-9861(92)90433-w

• Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

  Chemical Research in Toxicology · 1992 · 10.1021/tx00030a017

• The double-edged role of nitric oxide in brain function and superoxide-mediated injury.

  PubMed · 1991

• Peroxynitrite oxidation of sulfhydryls.

  Journal of Biological Chemistry · 1991 · https://doi.org/10.1016/s0021-9258(20)64313-7

• Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

  Proceedings of the National Academy of Sciences · 1990 · https://doi.org/10.1073/pnas.87.4.1620

• Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance.

  Journal of Biological Chemistry · 1988 · 10.1016/s0021-9258(18)68727-7

Current projects

No projects listed.