William E. Evans

Research interests

Publications

• Multiplex assessment of protein variant abundance by massively parallel sequencing

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0122-z

• Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT 15 Genotypes: 2018 Update

  Clinical Pharmacology & Therapeutics · 2018 · https://doi.org/10.1002/cpt.1304

• NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3508

• Pharmacogenomics in the clinic

  Nature · 2015 · https://doi.org/10.1038/nature15817

• Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.59.1636

• Preemptive Clinical Pharmacogenetics Implementation: Current Programs in Five US Medical Centers

  The Annual Review of Pharmacology and Toxicology · 2014 · https://doi.org/10.1146/annurev-pharmtox-010814-124835

• Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2014 · https://doi.org/10.1056/nejmoa1403088

• The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

  Nature · 2012 · https://doi.org/10.1038/nature10725

• Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

  Blood · 2012 · https://doi.org/10.1182/blood-2012-05-378943

• Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

  Clinical Pharmacology & Therapeutics · 2011 · https://doi.org/10.1038/clpt.2010.320

• Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0900386

• A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

  The Lancet Oncology · 2009 · https://doi.org/10.1016/s1470-2045(08)70339-5

• Germline genomic variants associated with childhood acute lymphoblastic leukemia

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.432

• Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

  Nature · 2007 · https://doi.org/10.1038/nature05690

• Treatment of Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2006 · https://doi.org/10.1056/nejmra052603

• Pharmacogenomics and Individualized Drug Therapy

  Annual Review of Medicine · 2005 · https://doi.org/10.1146/annurev.med.56.082103.104724

• Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment

  New England Journal of Medicine · 2004 · https://doi.org/10.1056/nejmoa033513

• Moving towards individualized medicine with pharmacogenomics

  Nature · 2004 · https://doi.org/10.1038/nature02626

• Pharmacogenomics — Drug Disposition, Drug Targets, and Side Effects

  New England Journal of Medicine · 2003 · https://doi.org/10.1056/nejmra020526

• Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

  Cancer Cell · 2002 · https://doi.org/10.1016/s1535-6108(02)00032-6

• Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

  Science · 1999 · https://doi.org/10.1126/science.286.5439.487

• Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 1998 · https://doi.org/10.1056/nejm199808273390907

• Conventional Compared with Individualized Chemotherapy for Childhood Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 1998 · https://doi.org/10.1056/nejm199802193380803

• Applied pharmacokinetics : principles of therapeutic drug monitoring

  Medical Entomology and Zoology · 1992

• Acute Myeloid Leukemia in Children Treated with Epipodophyllotoxins for Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 1991 · https://doi.org/10.1056/nejm199112123252402

Current projects

No projects listed.