Douglas R. Green

Research interests

Publications

• Apoptotic cell death in disease—Current understanding of the NCCD 2023

  Cell Death and Differentiation · 2023 · https://doi.org/10.1038/s41418-023-01153-w

• Autophagy in major human diseases

  The EMBO Journal · 2021 · https://doi.org/10.15252/embj.2021108863

• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

  Cell Death and Differentiation · 2018 · https://doi.org/10.1038/s41418-017-0012-4

• Molecular definitions of autophagy and related processes

  The EMBO Journal · 2017 · https://doi.org/10.15252/embj.201796697

• Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1403252111

• C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma

  Nature · 2014 · https://doi.org/10.1038/nature13109

• Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

  Cell Death and Differentiation · 2014 · https://doi.org/10.1038/cdd.2014.137

• Synchronized renal tubular cell death involves ferroptosis

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1415518111

• Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

  Nature Immunology · 2013 · https://doi.org/10.1038/ni.2563

• Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

  Cell Death and Differentiation · 2011 · 10.1038/cdd.2011.96

• HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

  The Journal of Experimental Medicine · 2011 · 10.1084/jem.20110278

• The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

  Immunity · 2011 · 10.1016/j.immuni.2011.09.021

• The BCL-2 Family Reunion

  Molecular Cell · 2010 · 10.1016/j.molcel.2010.01.025

• Mitochondria and cell death: outer membrane permeabilization and beyond

  Nature Reviews Molecular Cell Biology · 2010 · 10.1038/nrm2952

• Immunogenic and tolerogenic cell death

  Nature reviews. Immunology · 2009 · 10.1038/nri2545

• Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

  Cell Death and Differentiation · 2008 · https://doi.org/10.1038/cdd.2008.150

• Chk1 Suppresses a Caspase-2 Apoptotic Response to DNA Damage that Bypasses p53, Bcl-2, and Caspase-3

  Cell · 2008 · https://doi.org/10.1016/j.cell.2008.03.037

• Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

  Science · 2004 · 10.1126/science.1092734

• The Pathophysiology of Mitochondrial Cell Death

  Science · 2004 · https://doi.org/10.1126/science.1099320

• Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

  Cell · 2002 · 10.1016/s0092-8674(02)01036-x

• Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

  Nature Cell Biology · 2000 · 10.1038/35019501

• Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

  The Journal of Cell Biology · 1999 · 10.1083/jcb.144.2.281

• Mitochondria and Apoptosis

  Science · 1998 · https://doi.org/10.1126/science.281.5381.1309

• The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

  Science · 1997 · https://doi.org/10.1126/science.275.5303.1132

• Suppression of TNF-α-Induced Apoptosis by NF-κB

  Science · 1996 · 10.1126/science.274.5288.787

• Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

  The Journal of Experimental Medicine · 1995 · 10.1084/jem.182.5.1545

• Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

  Science · 1995 · 10.1126/science.270.5239.1189

Current projects

No projects listed.