Mary V. Relling

Research interests

Publications

• PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-018-0315-5

• Standardizing CYP 2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group

  Clinical and Translational Science · 2019 · 10.1111/cts.12692

• Multiplex assessment of protein variant abundance by massively parallel sequencing

  Nature Genetics · 2018 · 10.1038/s41588-018-0122-z

• Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT 15 Genotypes: 2018 Update

  Clinical Pharmacology & Therapeutics · 2018 · https://doi.org/10.1002/cpt.1304

• The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3909

• Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC)

  Genetics in Medicine · 2016 · 10.1038/gim.2016.87

• Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration

  Journal of Clinical Oncology · 2015 · 10.1200/jco.2014.59.1636

• Pharmacogenomics in the clinic

  Nature · 2015 · 10.1038/nature15817

• Preemptive Clinical Pharmacogenetics Implementation: Current Programs in Five US Medical Centers

  The Annual Review of Pharmacology and Toxicology · 2014 · 10.1146/annurev-pharmtox-010814-124835

• Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2014 · https://doi.org/10.1056/nejmoa1403088

• Implementing genomic medicine in the clinic: the future is here

  Genetics in Medicine · 2013 · 10.1038/gim.2012.157

• Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

  Clinical Pharmacology & Therapeutics · 2011 · 10.1038/clpt.2010.320

• Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

  New England Journal of Medicine · 2009 · 10.1056/nejmoa0900386

• Germline genomic variants associated with childhood acute lymphoblastic leukemia

  Nature Genetics · 2009 · 10.1038/ng.432

• Deletion of IKZF1 and Prognosis in Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0808253

• BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

  Nature · 2008 · 10.1038/nature06866

• Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

  Nature · 2007 · 10.1038/nature05690

• Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment

  New England Journal of Medicine · 2004 · 10.1056/nejmoa033513

• Acute Lymphoblastic Leukemia

  New England Journal of Medicine · 2004 · 10.1056/nejmra023001

• Moving towards individualized medicine with pharmacogenomics

  Nature · 2004 · 10.1038/nature02626

• Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

  Cancer Cell · 2002 · 10.1016/s1535-6108(02)00032-6

• Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

  Nature Genetics · 2001 · 10.1038/86882

• Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics

  Science · 1999 · 10.1126/science.286.5439.487

• Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus

  JNCI Journal of the National Cancer Institute · 1999 · 10.1093/jnci/91.23.2001

• Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance

  Annals of Internal Medicine · 1997 · 10.7326/0003-4819-126-8-199704150-00003

Current projects

No projects listed.