Paul G. Thomas

Research interests

Publications

• Principles and therapeutic applications of adaptive immunity

  Cell · 2024 · 10.1016/j.cell.2024.03.037

• Mucosal immune responses to infection and vaccination in the respiratory tract

  Immunity · 2022 · 10.1016/j.immuni.2022.04.013

• ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

  Nature · 2022 · 10.1038/s41586-022-04753-7

• SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans

  Cell · 2021 · 10.1016/j.cell.2021.12.026

• Impact of the COVID-19 nonpharmaceutical interventions on influenza and other respiratory viral infections in New Zealand

  Nature Communications · 2021 · 10.1038/s41467-021-21157-9

• Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract

  Nature Reviews Microbiology · 2021 · 10.1038/s41579-021-00542-7

• Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

  Cell · 2020 · 10.1016/j.cell.2020.02.050

• Influenza virus-related critical illness: pathophysiology and epidemiology

  Critical Care · 2019 · 10.1186/s13054-019-2539-x

• Understanding the drivers of MHC restriction of T cell receptors

  Nature reviews. Immunology · 2018 · 10.1038/s41577-018-0007-5

• De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation

  Cell · 2017 · 10.1016/j.cell.2017.06.007

• VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

  Nucleic Acids Research · 2017 · 10.1093/nar/gkx760

• New fronts emerge in the influenza cytokine storm

  Seminars in Immunopathology · 2017 · 10.1007/s00281-017-0636-y

• Quantifiable predictive features define epitope-specific T cell receptor repertoires

  Nature · 2017 · 10.1038/nature22383

• Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination

  Nature Immunology · 2016 · 10.1038/ni.3533

• RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus

  Cell Host & Microbe · 2016 · 10.1016/j.chom.2016.05.011

• DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

  Cell Host & Microbe · 2016 · 10.1016/j.chom.2016.09.014

• Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8+ T cells

  Nature Communications · 2015 · 10.1038/ncomms7833

• Cytomegalovirus infection enhances the immune response to influenza

  Science Translational Medicine · 2015 · 10.1126/scitranslmed.aaa2293

• Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

  Nature Immunology · 2013 · 10.1038/ni.2563

• Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

  The Journal of Immunology · 2013 · 10.4049/jimmunol.1300014

• The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

  Immunity · 2009 · https://doi.org/10.1016/j.immuni.2009.02.006

• TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

  Proceedings of the National Academy of Sciences · 2009 · 10.1073/pnas.0900655106

• Influenza and the challenge for immunology

  Nature Immunology · 2006 · 10.1038/ni1343

• Cell-mediated Protection in Influenza Infection

  Emerging infectious diseases · 2006 · 10.3201/eid1201.051237

• Maturation of Dendritic Cell 2 Phenotype by a Helminth Glycan Uses a Toll-Like Receptor 4-Dependent Mechanism

  The Journal of Immunology · 2003 · 10.4049/jimmunol.171.11.5837

Current projects

No projects listed.