Rik Vandenberghe

Research interests

Publications

• Temporal order of clinical and biomarker changes in familial frontotemporal dementia

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01942-9

• Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

  Neurology · 2021 · https://doi.org/10.1212/wnl.0000000000011848

• Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia

  Journal of Neurology Neurosurgery & Psychiatry · 2020 · https://doi.org/10.1136/jnnp-2019-321954

• Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders

  Brain · 2020 · https://doi.org/10.1093/brain/awaa018

• Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0358-2

• Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0495-7

• Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30394-1

• Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30354-0

• Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease

  New England Journal of Medicine · 2018 · https://doi.org/10.1056/nejmoa1706441

• Prevalence of amyloid‐β pathology in distinct variants of primary progressive aphasia

  Annals of Neurology · 2018 · https://doi.org/10.1002/ana.25333

• Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

  JAMA Psychiatry · 2017 · https://doi.org/10.1001/jamapsychiatry.2017.3391

• Consensus classification of posterior cortical atrophy

  Alzheimer s & Dementia · 2017 · https://doi.org/10.1016/j.jalz.2017.01.014

• Neurofilament light chain: a biomarker for genetic frontotemporal dementia

  Annals of Clinical and Translational Neurology · 2016 · https://doi.org/10.1002/acn3.325

• Prevalence of Amyloid PET Positivity in Dementia Syndromes

  JAMA · 2015 · https://doi.org/10.1001/jama.2015.4669

• Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

  Acta Neuropathologica · 2014 · https://doi.org/10.1007/s00401-014-1298-7

• A Pan‐ E uropean Study of the C9orf72 Repeat Associated with FTLD : Geographic Prevalence, Genomic Instability, and Intermediate Repeats

  Human Mutation · 2012 · https://doi.org/10.1002/humu.22244

• Classification of primary progressive aphasia and its variants

  Neurology · 2011 · https://doi.org/10.1212/wnl.0b013e31821103e6

• 18 F‐flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial

  Annals of Neurology · 2010 · 10.1002/ana.22068

• Phase 1 Study of the Pittsburgh Compound B Derivative 18 F-Flutemetamol in Healthy Volunteers and Patients with Probable Alzheimer Disease

  Journal of Nuclear Medicine · 2009 · https://doi.org/10.2967/jnumed.109.063305

• Whole-Body Biodistribution and Radiation Dosimetry of 18F-GE067: A Radioligand for In Vivo Brain Amyloid Imaging

  Journal of Nuclear Medicine · 2009 · https://doi.org/10.2967/jnumed.108.060756

Current projects

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