Alexa B. Kimball

Research interests

Publications

• Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised, placebo-controlled, double-blind phase 3 trials

  The Lancet · 2023 · https://doi.org/10.1016/s0140-6736(23)00022-3

• Hidradenitis suppurativa

  Nature Reviews Disease Primers · 2020 · https://doi.org/10.1038/s41572-020-0149-1

• What causes hidradenitis suppurativa ?—15 years after

  Experimental Dermatology · 2020 · https://doi.org/10.1111/exd.14214

• Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization – systematic review and recommendations from the HS ALLIANCE working group

  Journal of the European Academy of Dermatology and Venereology · 2018 · https://doi.org/10.1111/jdv.15233

• Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active comparator–controlled VOYAGE 1 trial

  Journal of the American Academy of Dermatology · 2017 · https://doi.org/10.1016/j.jaad.2016.11.041

• Tildrakizumab versus placebo or etanercept for chronic plaque psoriasis (reSURFACE 1 and reSURFACE 2): results from two randomised controlled, phase 3 trials

  The Lancet · 2017 · https://doi.org/10.1016/s0140-6736(17)31279-5

• Development and validation of the International Hidradenitis Suppurativa Severity Score System ( IHS 4), a novel dynamic scoring system to assess HS severity

  British Journal of Dermatology · 2017 · https://doi.org/10.1111/bjd.15748

• Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1504370

• Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis

  New England Journal of Medicine · 2015 · https://doi.org/10.1056/nejmoa1503824

• Hidradenitis suppurativa: Epidemiology and scope of the problem

  Journal of the American Academy of Dermatology · 2015 · https://doi.org/10.1016/j.jaad.2015.07.052

• HiSCR (Hidradenitis Suppurativa Clinical Response): a novel clinical endpoint to evaluate therapeutic outcomes in patients with hidradenitis suppurativa from the placebo‐controlled portion of a phase 2 adalimumab study

  Journal of the European Academy of Dermatology and Venereology · 2015 · https://doi.org/10.1111/jdv.13216

• Assessing the validity, responsiveness and meaningfulness of the Hidradenitis Suppurativa Clinical Response (HiSCR) as the clinical endpoint for hidradenitis suppurativa treatment

  British Journal of Dermatology · 2014 · https://doi.org/10.1111/bjd.13270

• Adalimumab for the Treatment of Moderate to Severe Hidradenitis Suppurativa

  Annals of Internal Medicine · 2012 · https://doi.org/10.7326/0003-4819-157-12-201212180-00004

• Association Between Biologic Therapies for Chronic Plaque Psoriasis and Cardiovascular Events

  JAMA · 2011 · https://doi.org/10.1001/jama.2011.1211

• Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebo-controlled phase III trial

  Journal of the American Academy of Dermatology · 2010 · https://doi.org/10.1016/j.jaad.2009.09.014

• Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

  The Lancet · 2008 · https://doi.org/10.1016/s0140-6736(08)60725-4

• Adalimumab therapy for moderate to severe psoriasis: A randomized, controlled phase III trial

  Journal of the American Academy of Dermatology · 2007 · https://doi.org/10.1016/j.jaad.2007.09.010

• IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2–dependent mechanisms with implications for psoriasis pathogenesis

  The Journal of Experimental Medicine · 2006 · https://doi.org/10.1084/jem.20060244

• The Psychosocial Burden of Psoriasis

  American Journal of Clinical Dermatology · 2005 · https://doi.org/10.2165/00128071-200506060-00005

Current projects

No projects listed.