Nathan I. Shapiro

Research interests

Publications

• Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults

  New England Journal of Medicine · 2023 · https://doi.org/10.1056/nejmoa2301601

• Redefining critical illness

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01843-x

• Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study

  BMJ · 2022 · https://doi.org/10.1136/bmj-2021-069761

• Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years — United States, January–March 2021

  MMWR Morbidity and Mortality Weekly Report · 2021 · https://doi.org/10.15585/mmwr.mm7018e1

• Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity

  JAMA · 2021 · https://doi.org/10.1001/jama.2021.19499

• Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network — United States, March–June 2020

  MMWR Morbidity and Mortality Weekly Report · 2020 · https://doi.org/10.15585/mmwr.mm6930e1

• Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19

  JAMA · 2020 · https://doi.org/10.1001/jama.2020.22240

• The glycocalyx: a novel diagnostic and therapeutic target in sepsis

  Critical Care · 2019 · https://doi.org/10.1186/s13054-018-2292-6

• Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine

  Intensive Care Medicine · 2018 · https://doi.org/10.1007/s00134-018-5070-7

• Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study

  Critical Care Medicine · 2017 · https://doi.org/10.1097/ccm.0000000000002321

• Creating an automated trigger for sepsis clinical decision support at emergency department triage using machine learning

  PLoS ONE · 2017 · https://doi.org/10.1371/journal.pone.0174708

• Diagnosing Appendicitis: Evidence-Based Review of the Diagnostic Approach in 2014

  Western Journal of Emergency Medicine · 2014 · https://doi.org/10.5811/westjem.2014.9.21568

• Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

  Critical Care · 2013 · https://doi.org/10.1186/cc12503

• Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest

  Circulation · 2011 · https://doi.org/10.1161/circulationaha.110.001016

• Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol*

  Critical Care Medicine · 2011 · https://doi.org/10.1097/ccm.0b013e31821e87ab

• The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis

  Critical Care · 2010 · 10.1186/cc9290

• Multicenter Study of Central Venous Oxygen Saturation (ScvO2) as a Predictor of Mortality in Patients With Sepsis

  Annals of Emergency Medicine · 2009 · 10.1016/j.annemergmed.2009.08.014

• MULTICENTER STUDY OF EARLY LACTATE CLEARANCE AS A DETERMINANT OF SURVIVAL IN PATIENTS WITH PRESUMED SEPSIS

  Shock · 2009 · https://doi.org/10.1097/shk.0b013e3181971d47

• Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis

  Intensive Care Medicine · 2008 · https://doi.org/10.1007/s00134-008-1193-6

• Who Needs a Blood Culture? A Prospectively Derived and Validated Prediction Rule

  Journal of Emergency Medicine · 2008 · https://doi.org/10.1016/j.jemermed.2008.04.001

• Occult hypoperfusion and mortality in patients with suspected infection

  Intensive Care Medicine · 2007 · https://doi.org/10.1007/s00134-007-0680-5

• National estimates of severe sepsis in United States emergency departments

  Critical Care Medicine · 2007 · https://doi.org/10.1097/01.ccm.0000277043.85378.c1

• Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol*

  Critical Care Medicine · 2006 · https://doi.org/10.1097/01.ccm.0000206104.18647.a8

• Serum Lactate as a Predictor of Mortality in Emergency Department Patients with Infection

  Annals of Emergency Medicine · 2005 · https://doi.org/10.1016/j.annemergmed.2004.12.006

• Mortality in Emergency Department Sepsis (MEDS) score: A prospectively derived and validated clinical prediction rule*

  Critical Care Medicine · 2003 · https://doi.org/10.1097/01.ccm.0000054867.01688.d1

Current projects

No projects listed.