Jonathan D. Smith

Research interests

Publications

• Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

  Nature Genetics · 2017 · 10.1038/ng.3843

• HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P 1 to limit vascular inflammation

  Science Signaling · 2015 · 10.1126/scisignal.aaa2581

• γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO

  Cell Metabolism · 2014 · 10.1016/j.cmet.2014.10.006

• An abundant dysfunctional apolipoprotein A1 in human atheroma

  Nature Medicine · 2014 · 10.1038/nm.3459

• Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

  Nature Medicine · 2013 · https://doi.org/10.1038/nm.3145

• Paradoxical Association of Enhanced Cholesterol Efflux With Increased Incident Cardiovascular Risks

  Arteriosclerosis Thrombosis and Vascular Biology · 2013 · 10.1161/atvbaha.113.301373

• Enhanced Condensation on Lubricant-Impregnated Nanotextured Surfaces

  ACS Nano · 2012 · 10.1021/nn303867y

• Vineland Adaptive Behavior Scales

  · 2012 · 10.1007/978-1-4419-1698-3_255

• Meta-analysis identifies six new susceptibility loci for atrial fibrillation

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2261

• Droplet mobility on lubricant-impregnated surfaces

  Soft Matter · 2012 · https://doi.org/10.1039/c2sm27032c

• High-Density Lipoprotein Function, Dysfunction, and Reverse Cholesterol Transport

  Arteriosclerosis Thrombosis and Vascular Biology · 2012 · 10.1161/atvbaha.112.300133

• Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

  Nature · 2011 · https://doi.org/10.1038/nature09922

• Frost formation and ice adhesion on superhydrophobic surfaces

  Applied Physics Letters · 2010 · 10.1063/1.3524513

• Relationships between Water Wettability and Ice Adhesion

  ACS Applied Materials & Interfaces · 2010 · 10.1021/am1006035

• Common variants in KCNN3 are associated with lone atrial fibrillation

  Nature Genetics · 2010 · 10.1038/ng.537

• Genome-wide association study of PR interval

  Nature Genetics · 2010 · 10.1038/ng.517

• ApoE Promotes the Proteolytic Degradation of Aβ

  Neuron · 2008 · 10.1016/j.neuron.2008.04.010

• Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease

  Journal of Clinical Investigation · 2004 · 10.1172/jci21109

• Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease

  Journal of Clinical Investigation · 2004 · 10.1172/jci200421109

• Alcohol Consumption Raises HDL Cholesterol Levels by Increasing the Transport Rate of Apolipoproteins A-I and A-II

  Circulation · 2000 · 10.1161/01.cir.102.19.2347

• Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

  Journal of Clinical Investigation · 2000 · https://doi.org/10.1172/jci9259

• T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse

  Proceedings of the National Academy of Sciences · 1997 · 10.1073/pnas.94.9.4642

• Apolipoprotein E allele–specific antioxidant activity and effects on cytotoxicity by oxidative insults and β–amyloid peptides

  Nature Genetics · 1996 · 10.1038/ng0996-55

• Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E.

  Proceedings of the National Academy of Sciences · 1995 · 10.1073/pnas.92.18.8264

• Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

  Cell · 1992 · 10.1016/0092-8674(92)90362-g

Current projects

No projects listed.