Matti Pirinen

Research interests

Publications

• A second update on mapping the human genetic architecture of COVID-19

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06355-3

• Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-021-00990-0

• The role of polygenic risk and susceptibility genes in breast cancer over the course of life

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-19966-5

• Genetic architecture of human plasma lipidome and its link to cardiovascular disease

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-11954-8

• FINEMAP: efficient variable selection using summary data from genome-wide association studies

  Bioinformatics · 2016 · https://doi.org/10.1093/bioinformatics/btw018

• Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms11122

• Effect of predicted protein-truncating genetic variants on the human transcriptome

  Science · 2015 · https://doi.org/10.1126/science.1261877

• The fine-scale genetic structure of the British population

  Nature · 2015 · https://doi.org/10.1038/nature14230

• Reappraisal of known malaria resistance loci in a large multicenter study

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.3107

• Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2770

• Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

  PLoS Genetics · 2013 · https://doi.org/10.1371/journal.pgen.1003509

• Transcriptome and genome sequencing uncovers functional variation in humans

  Nature · 2013 · https://doi.org/10.1038/nature12531

• Bayesian refinement of association signals for 14 loci in 3 common diseases

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2435

• Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2408

• Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

  Nature Genetics · 2011 · 10.1038/ng.873

• Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

  Nature · 2011 · https://doi.org/10.1038/nature10251

• A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.694

Current projects

No projects listed.