Pirro G. Hysi

Research interests

Publications

• A foundation model for generalizable disease detection from retinal images

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06555-x

• Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-020-20851-4

• Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

  Nature Genetics · 2020 · 10.1038/s41588-020-0599-0

• Real-time tracking of self-reported symptoms to predict potential COVID-19

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-0916-2

• Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

  Nature Genetics · 2020 · 10.1038/s41588-019-0556-y

• Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

  Science · 2019 · https://doi.org/10.1126/science.aav7188

• Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

  Nature Genetics · 2018 · 10.1038/s41588-018-0126-8

• Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

  Nature Genetics · 2018 · 10.1038/s41588-018-0127-7

• New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

  Human Molecular Genetics · 2016 · https://doi.org/10.1093/hmg/ddw399

• Correction: Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

  Nature Communications · 2016 · 10.1038/ncomms11270

• New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

  Nature Communications · 2016 · 10.1038/ncomms10495

• Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

  Nature Genetics · 2016 · 10.1038/ng.3482

• The UK10K project identifies rare variants in health and disease

  Nature · 2015 · 10.1038/nature14962

• Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

  Nature Genetics · 2015 · 10.1038/ng.3424

• Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

  Nature Communications · 2015 · 10.1038/ncomms9111

• Increasing Prevalence of Myopia in Europe and the Impact of Education

  Ophthalmology · 2015 · https://doi.org/10.1016/j.ophtha.2015.03.018

• Low copy number of the salivary amylase gene predisposes to obesity

  Nature Genetics · 2014 · 10.1038/ng.2939

• Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.3087

• Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

  The American Journal of Human Genetics · 2013 · https://doi.org/10.1016/j.ajhg.2013.06.016

• Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

  Nature Genetics · 2013 · 10.1038/ng.2506

• Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study

  The Lancet Respiratory Medicine · 2013 · 10.1016/s2213-2600(13)70045-6

• Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

  Nature Genetics · 2013 · 10.1038/ng.2554

• A Genome-Wide Association Study Identifies Five Loci Influencing Facial Morphology in Europeans

  PLoS Genetics · 2012 · 10.1371/journal.pgen.1002932

• Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma

  PLoS Genetics · 2012 · https://doi.org/10.1371/journal.pgen.1002611

• Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

  Nature Genetics · 2011 · 10.1038/ng.1017

• Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

  Nature Genetics · 2011 · 10.1038/ng.941

• Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

  Human Molecular Genetics · 2005 · 10.1093/hmg/ddi135

• NOD1 variation, immunoglobulin E and asthma

  Human Molecular Genetics · 2005 · 10.1093/hmg/ddi087

Current projects

No projects listed.