Ravindra K. Gupta

Research interests

Publications

• Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75

  Cell Host & Microbe · 2022 · 10.1016/j.chom.2022.09.018

• SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies

  Nature Reviews Microbiology · 2022 · 10.1038/s41579-022-00809-7

• FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2

  Nature · 2022 · https://doi.org/10.1038/s41586-022-05594-0

• The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK

  Virus Evolution · 2022 · https://doi.org/10.1093/ve/veac080

• SARS-CoV-2 B.1.617 Mutations L452R and E484Q Are Not Synergistic for Antibody Evasion

  The Journal of Infectious Diseases · 2021 · https://doi.org/10.1093/infdis/jiab368

• Investigate the origins of COVID-19

  Science · 2021 · 10.1126/science.abj0016

• The biological and clinical significance of emerging SARS-CoV-2 variants

  Nature Reviews Genetics · 2021 · https://doi.org/10.1038/s41576-021-00408-x

• The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.09.003

• Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

  Immunity · 2021 · https://doi.org/10.1016/j.immuni.2021.05.010

• Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India

  Science · 2021 · https://doi.org/10.1126/science.abj9932

• The effect of spike mutations on SARS-CoV-2 neutralization

  Cell Reports · 2021 · 10.1016/j.celrep.2021.108890

• Will SARS-CoV-2 variants of concern affect the promise of vaccines?

  Nature reviews. Immunology · 2021 · 10.1038/s41577-021-00556-5

• SARS-CoV-2 variants, spike mutations and immune escape

  Nature Reviews Microbiology · 2021 · https://doi.org/10.1038/s41579-021-00573-0

• The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s

  Nature Communications · 2020 · 10.1038/s41467-020-19170-5

• Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation

  medRxiv · 2020 · 10.1101/2020.12.05.20241927

• Evidence for HIV-1 cure after CCR5Δ32/Δ32 allogeneic haemopoietic stem-cell transplantation 30 months post analytical treatment interruption: a case report

  The Lancet HIV · 2020 · 10.1016/s2352-3018(20)30069-2

• Recurrent emergence and transmission of a SARS-CoV-2 spike deletion H69/V70

  bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 10.1101/2020.12.14.422555

• HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

  Nature · 2019 · 10.1038/s41586-019-1027-4

• HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis

  The Lancet Infectious Diseases · 2017 · https://doi.org/10.1016/s1473-3099(17)30702-8

• Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

  The Lancet Infectious Diseases · 2016 · https://doi.org/10.1016/s1473-3099(15)00536-8

• The “Silent” Global Burden of Congenital Cytomegalovirus

  Clinical Microbiology Reviews · 2013 · https://doi.org/10.1128/cmr.00062-12

• Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global collaborative study and meta-regression analysis

  The Lancet · 2012 · 10.1016/s0140-6736(12)61038-1

• Mutation of a Single Residue Renders Human Tetherin Resistant to HIV-1 Vpu-Mediated Depletion

  PLoS Pathogens · 2009 · 10.1371/journal.ppat.1000443

• Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysis

  The Lancet Infectious Diseases · 2009 · 10.1016/s1473-3099(09)70136-7

• Emergence of Drug Resistance in HIV Type 1–Infected Patients after Receipt of First‐Line Highly Active Antiretroviral Therapy: A Systematic Review of Clinical Trials

  Clinical Infectious Diseases · 2008 · 10.1086/590943

Current projects

No projects listed.