David Cunningham

Research interests

Publications

• Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study

  The Lancet Oncology · 2019 · https://doi.org/10.1016/s1470-2045(18)30915-x

• Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial

  The Lancet Oncology · 2019 · https://doi.org/10.1016/s1470-2045(19)30027-0

• Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

  Science · 2018 · https://doi.org/10.1126/science.aao2774

• Oesophageal cancer

  The Lancet · 2017 · 10.1016/s0140-6736(17)31462-9

• Oesophageal cancer

  Nature Reviews Disease Primers · 2017 · 10.1038/nrdp.2017.48

• Brentuximab Vedotin with Chemotherapy for Stage III or IV Hodgkin’s Lymphoma

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1708984

• Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial

  The Lancet · 2017 · https://doi.org/10.1016/s0140-6736(16)32409-6

• Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

  Annals of Oncology · 2016 · 10.1093/annonc/mdw350

• Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial

  The Lancet · 2015 · 10.1016/s0140-6736(15)00986-1

• Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial

  The Lancet Oncology · 2014 · https://doi.org/10.1016/s1470-2045(14)70420-6

• Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

  New England Journal of Medicine · 2013 · 10.1056/nejmoa1305275

• Cetuximab Plus Irinotecan, Fluorouracil, and Leucovorin As First-Line Treatment for Metastatic Colorectal Cancer: Updated Analysis of Overall Survival According to Tumor KRAS and BRAF Mutation Status

  Journal of Clinical Oncology · 2011 · 10.1200/jco.2010.33.5091

• SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

  Journal of Biological Chemistry · 2010 · 10.1074/jbc.m109.088682

• Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study

  Journal of Clinical Oncology · 2010 · 10.1200/jco.2009.27.4860

• Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection

  JAMA · 2010 · 10.1001/jama.2010.1275

• Colorectal cancer

  The Lancet · 2010 · 10.1016/s0140-6736(10)60353-4

• Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

  Annals of Oncology · 2010 · 10.1093/annonc/mdq164

• Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer

  New England Journal of Medicine · 2010 · https://doi.org/10.1056/nejmoa0908721

• Prognostic Role of KRAS and BRAF in Stage II and III Resected Colon Cancer: Results of the Translational Study on the PETACC-3, EORTC 40993, SAKK 60-00 Trial

  Journal of Clinical Oncology · 2009 · 10.1200/jco.2009.23.3452

• Capecitabine and Oxaliplatin for Advanced Esophagogastric Cancer

  New England Journal of Medicine · 2008 · 10.1056/nejmoa073149

• The role of probiotics in aquaculture

  Veterinary Microbiology · 2006 · 10.1016/j.vetmic.2006.01.009

• Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer

  New England Journal of Medicine · 2006 · https://doi.org/10.1056/nejmoa055531

• Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer

  New England Journal of Medicine · 2004 · https://doi.org/10.1056/nejmoa033025

• Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

  The Lancet · 2000 · https://doi.org/10.1016/s0140-6736(00)02034-1

• A Prognostic Score for Advanced Hodgkin's Disease

  New England Journal of Medicine · 1998 · 10.1056/nejm199811193392104

• Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

  The Lancet · 1998 · 10.1016/s0140-6736(98)02309-5

Current projects

No projects listed.