Malcolm J. Moore

Research interests

Publications

• Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial

  Clinical Cancer Research · 2017 · 10.1158/1078-0432.ccr-17-2994

• Germline BRCA Mutations in a Large Clinic-Based Cohort of Patients With Pancreatic Adenocarcinoma

  Journal of Clinical Oncology · 2015 · 10.1200/jco.2014.59.7401

• Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17

  European Journal of Cancer · 2015 · 10.1016/j.ejca.2015.03.015

• Early palliative care for patients with advanced cancer: a cluster-randomised controlled trial

  The Lancet · 2014 · https://doi.org/10.1016/s0140-6736(13)62416-2

• Overall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers

  British Journal of Cancer · 2014 · 10.1038/bjc.2014.418

• Pancreatic Cancer hENT1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial

  JNCI Journal of the National Cancer Institute · 2013 · 10.1093/jnci/djt347

• Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

  New England Journal of Medicine · 2013 · https://doi.org/10.1056/nejmoa1304369

• Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial

  The Lancet Oncology · 2012 · https://doi.org/10.1016/s1470-2045(12)70509-0

• Effect of Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid or Gemcitabine vs Observation on Survival in Patients With Resected Periampullary Adenocarcinoma

  JAMA · 2012 · 10.1001/jama.2012.7352

• DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy

  JNCI Journal of the National Cancer Institute · 2011 · 10.1093/jnci/djr153

• Advanced pancreatic carcinoma: current treatment and future challenges

  Nature Reviews Clinical Oncology · 2010 · 10.1038/nrclinonc.2009.236

• Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection

  JAMA · 2010 · https://doi.org/10.1001/jama.2010.1275

• Phase III Trial of Bevacizumab in Combination With Gemcitabine and Erlotinib in Patients With Metastatic Pancreatic Cancer

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2008.20.0238

• K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer

  New England Journal of Medicine · 2008 · https://doi.org/10.1056/nejmoa0804385

• Adjuvant Chemotherapy After Potentially Curative Resection of Metastases From Colorectal Cancer: A Pooled Analysis of Two Randomized Trials

  Journal of Clinical Oncology · 2008 · 10.1200/jco.2008.17.3781

• Erlotinib Plus Gemcitabine Compared With Gemcitabine Alone in Patients With Advanced Pancreatic Cancer: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group

  Journal of Clinical Oncology · 2007 · https://doi.org/10.1200/jco.2006.07.9525

• Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Sorafenib: A Review of Four Phase I Trials in Patients with Advanced Refractory Solid Tumors

  The Oncologist · 2007 · 10.1634/theoncologist.12-4-426

• Cetuximab for the Treatment of Colorectal Cancer

  New England Journal of Medicine · 2007 · 10.1056/nejmoa071834

• Long-Term Survival Results of a Randomized Trial Comparing Gemcitabine Plus Cisplatin, With Methotrexate, Vinblastine, Doxorubicin, Plus Cisplatin in Patients With Bladder Cancer

  Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.07.757

• Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

  New England Journal of Medicine · 2003 · 10.1056/nejmoa022289

• Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer

  New England Journal of Medicine · 2000 · https://doi.org/10.1056/nejm200009283431302

• Gemcitabine and Cisplatin Versus Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Advanced or Metastatic Bladder Cancer: Results of a Large, Randomized, Multinational, Multicenter, Phase III Study

  Journal of Clinical Oncology · 2000 · 10.1200/jco.2000.18.17.3068

• Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.

  Journal of Clinical Oncology · 1997 · https://doi.org/10.1200/jco.1997.15.6.2403

• A phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer

  Annals of Oncology · 1996 · 10.1093/oxfordjournals.annonc.a010600

• Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points.

  Journal of Clinical Oncology · 1996 · 10.1200/jco.1996.14.6.1756

Current projects

No projects listed.