Peter Paul De Deyn

Research interests

Publications

• Donanemab in Early Symptomatic Alzheimer Disease

  JAMA · 2023 · https://doi.org/10.1001/jama.2023.13239

• Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease: a phase 1b, randomized, placebo-controlled trial

  Nature Medicine · 2023 · 10.1038/s41591-023-02326-3

• Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

  Acta Neuropathologica · 2021 · 10.1007/s00401-021-02263-w

• PTZ-induced seizures in mice require a revised Racine scale

  Epilepsy & Behavior · 2019 · 10.1016/j.yebeh.2019.02.029

• Rapid Reconfiguration of the Functional Connectome after Chemogenetic Locus Coeruleus Activation

  Neuron · 2019 · 10.1016/j.neuron.2019.05.034

• Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target

  Frontiers in Immunology · 2019 · 10.3389/fimmu.2019.02565

• Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

  Molecular Psychiatry · 2013 · 10.1038/mp.2013.1

• APOE and Alzheimer disease: a major gene with semi-dominant inheritance

  Molecular Psychiatry · 2011 · https://doi.org/10.1038/mp.2011.52

• Monitoring of Physical Activity After Stroke: A Systematic Review of Accelerometry-Based Measures

  Archives of Physical Medicine and Rehabilitation · 2010 · 10.1016/j.apmr.2009.10.025

• Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.439

• The complexity of neurobiological processes in acute ischemic stroke

  Clinical Neurology and Neurosurgery · 2009 · 10.1016/j.clineuro.2009.04.001

• Cerebellar neurocognition: Insights into the bottom of the brain

  Clinical Neurology and Neurosurgery · 2008 · 10.1016/j.clineuro.2008.05.013

• Neuropsychiatric Syndromes in Dementia

  Dementia and Geriatric Cognitive Disorders · 2007 · 10.1159/000110738

• Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia

  Neurobiology of Aging · 2007 · 10.1016/j.neurobiolaging.2007.02.016

• Decreased expression of the GABAA receptor in fragile X syndrome

  Brain Research · 2006 · 10.1016/j.brainres.2006.08.115

• Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: frequency, profile and associated care giver stress

  Journal of Neurology Neurosurgery & Psychiatry · 2006 · 10.1136/jnnp.2005.083113

• Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

  Nature · 2006 · https://doi.org/10.1038/nature05017

• Neurological complications in renal failure: a review

  Clinical Neurology and Neurosurgery · 2004 · 10.1016/j.clineuro.2004.07.012

• Age‐dependent cognitive decline in the APP23 model precedes amyloid deposition

  European Journal of Neuroscience · 2003 · 10.1046/j.1460-9568.2003.02444.x

• Review on uremic toxins: Classification, concentration, and interindividual variability

  Kidney International · 2003 · https://doi.org/10.1046/j.1523-1755.2003.00924.x

• Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion

  Cell and Tissue Research · 2002 · 10.1007/s00441-002-0651-7

• Applications of the Morris water maze in the study of learning and memory

  Brain Research Reviews · 2001 · https://doi.org/10.1016/s0165-0173(01)00067-4

• The Lateralized Linguistic Cerebellum: A Review and a New Hypothesis

  Brain and Language · 2001 · 10.1006/brln.2001.2569

• A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia

  Neurology · 1999 · 10.1212/wnl.53.5.946

• Phenotype of arylsulfatase A-deficient mice: Relationship to human metachromatic leukodystrophy

  Proceedings of the National Academy of Sciences · 1996 · 10.1073/pnas.93.25.14821

Current projects

No projects listed.