Rinse K. Weersma

Research interests

Publications

• Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-023-01384-0

• Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00950-8

• Interaction between drugs and the gut microbiome

  Gut · 2020 · https://doi.org/10.1136/gutjnl-2019-320204

• Gut microbiome structure and metabolic activity in inflammatory bowel disease

  Nature Microbiology · 2018 · https://doi.org/10.1038/s41564-018-0306-4

• Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.02.038

• Fine-mapping inflammatory bowel disease loci to single-variant resolution

  Nature · 2017 · https://doi.org/10.1038/nature22969

• Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

  Nature Genetics · 2016 · 10.1038/ng.3528

• Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

  Science · 2016 · https://doi.org/10.1126/science.aad3369

• The effect of host genetics on the gut microbiome

  Nature Genetics · 2016 · 10.1038/ng.3663

• Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

  Gut · 2016 · 10.1136/gutjnl-2016-312135

• Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3745

• The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids

  Circulation Research · 2015 · 10.1161/circresaha.115.306807

• Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3359

• Proton pump inhibitors affect the gut microbiome

  Gut · 2015 · 10.1136/gutjnl-2015-310376

• Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

  The Lancet · 2015 · 10.1016/s0140-6736(15)00465-1

• Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies

  Gastroenterology · 2013 · https://doi.org/10.1053/j.gastro.2013.04.040

• Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis

  Hepatology · 2013 · https://doi.org/10.1002/hep.26565

• Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

  Journal of Hepatology · 2012 · https://doi.org/10.1016/j.jhep.2012.03.031

• Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Nature · 2012 · https://doi.org/10.1038/nature11582

• Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.728

• Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.717

• Genome-wide association identifies multiple ulcerative colitis susceptibility loci

  Nature Genetics · 2010 · 10.1038/ng.549

• Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.716

• Multiple common variants for celiac disease influencing immune gene expression

  Nature Genetics · 2010 · 10.1038/ng.543

• Genome-Wide Association Analysis in Primary Sclerosing Cholangitis

  Gastroenterology · 2009 · https://doi.org/10.1053/j.gastro.2009.11.046

• Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

  Nature Genetics · 2008 · 10.1038/ng.221

Current projects

No projects listed.