Nicholas D. Socci

Research interests

Publications

• Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade

  JAMA Oncology · 2018 · https://doi.org/10.1001/jamaoncol.2018.5801

• Molecular Determinants of Response to Anti–Programmed Cell Death (PD)-1 and Anti–Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non–Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing

  Journal of Clinical Oncology · 2018 · https://doi.org/10.1200/jco.2017.75.3384

• Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma–like and Non–Small Cell Carcinoma–like Subsets

  Clinical Cancer Research · 2016 · https://doi.org/10.1158/1078-0432.ccr-15-2946

• Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

  Nature Biotechnology · 2015 · https://doi.org/10.1038/nbt.3391

• A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2969

• A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2754

• Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

  New England Journal of Medicine · 2012 · https://doi.org/10.1056/nejmoa1112304

• Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2413

• Optimization of Dosing for EGFR-Mutant Non–Small Cell Lung Cancer with Evolutionary Cancer Modeling

  Science Translational Medicine · 2011 · https://doi.org/10.1126/scitranslmed.3002356

• Identification of a novel, recurrent HEY1‐NCOA2 fusion in mesenchymal chondrosarcoma based on a genome‐wide screen of exon‐level expression data

  Genes Chromosomes and Cancer · 2011 · https://doi.org/10.1002/gcc.20937

• Integrative Genomic Profiling of Human Prostate Cancer

  Cancer Cell · 2010 · 10.1016/j.ccr.2010.05.026

• A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

  Cell · 2007 · 10.1016/j.cell.2007.04.040

• Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

  Journal of Clinical Investigation · 2004 · https://doi.org/10.1172/jci200419511

• Site and mechanism of leptin action in a rodent form of congenital lipodystrophy

  Journal of Clinical Investigation · 2004 · https://doi.org/10.1172/jci19511

Current projects

No projects listed.