Per‐Olof Berggren

Research interests

Publications

• Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

  Cell Metabolism · 2018 · https://doi.org/10.1016/j.cmet.2018.01.004

• Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

  Cell Metabolism · 2018 · https://doi.org/10.1016/j.cmet.2018.01.015

• Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells

  Cell Reports · 2016 · https://doi.org/10.1016/j.celrep.2016.11.072

• Adipsin Is an Adipokine that Improves β Cell Function in Diabetes

  Cell · 2014 · https://doi.org/10.1016/j.cell.2014.06.005

• Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas

  Cell Metabolism · 2011 · https://doi.org/10.1016/j.cmet.2011.05.008

• Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

  Nature Medicine · 2011 · https://doi.org/10.1038/nm.2371

• Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action

  Cell Metabolism · 2010 · https://doi.org/10.1016/j.cmet.2010.06.011

• Insulin Signaling in the Pancreatic β-Cell

  Annual Review of Nutrition · 2008 · https://doi.org/10.1146/annurev.nutr.28.061807.155530

• Glutamate Is a Positive Autocrine Signal for Glucagon Release

  Cell Metabolism · 2008 · https://doi.org/10.1016/j.cmet.2008.03.004

• Noninvasive in vivo imaging of pancreatic islet cell biology

  Nature Medicine · 2008 · https://doi.org/10.1038/nm1701

• Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic β Cells

  Science · 2007 · https://doi.org/10.1126/science.1146824

• The Role of Voltage-Gated Calcium Channels in Pancreatic β-Cell Physiology and Pathophysiology

  Endocrine Reviews · 2006 · https://doi.org/10.1210/er.2005-0888

• The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

  Proceedings of the National Academy of Sciences · 2006 · https://doi.org/10.1073/pnas.0510790103

• A Novel Method for the Assessment of Cellular Composition and Beta-Cell Viability in Human Islet Preparations

  American Journal of Transplantation · 2005 · https://doi.org/10.1111/j.1600-6143.2005.00913.x

• SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

  The Journal of General Physiology · 2003 · https://doi.org/10.1085/jgp.20028707

• Sulfonylurea Receptor Type 1 Knock-out Mice Have Intact Feeding-stimulated Insulin Secretion despite Marked Impairment in Their Response to Glucose

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m206757200

• Selective Insulin Signaling through A and B Insulin Receptors Regulates Transcription of Insulin and Glucokinase Genes in Pancreatic β Cells

  Molecular Cell · 2001 · https://doi.org/10.1016/s1097-2765(01)00203-9

• Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes

  Nature Genetics · 2000 · https://doi.org/10.1038/81649

• Dopamine-induced Endocytosis of Na+,K+-ATPase Is Initiated by Phosphorylation of Ser-18 in the Rat α Subunit and Is Responsible for the Decreased Activity in Epithelial Cells

  Journal of Biological Chemistry · 1999 · https://doi.org/10.1074/jbc.274.4.1920

• Exocytosis of Insulin Promotes Insulin Gene Transcription via the Insulin Receptor/PI-3 Kinase/p70 s6 Kinase and CaM Kinase Pathways

  Molecular Cell · 1998 · https://doi.org/10.1016/s1097-2765(00)80093-3

• Glucose and Tolbutamide Induce Apoptosis in Pancreatic β-Cells

  Journal of Biological Chemistry · 1998 · https://doi.org/10.1074/jbc.273.50.33501

• PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic β Cells

  Science · 1996 · https://doi.org/10.1126/science.271.5250.813

• Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells.

  Proceedings of the National Academy of Sciences · 1994 · https://doi.org/10.1073/pnas.91.26.12487

• Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

  Nature · 1989 · https://doi.org/10.1038/341233a0

• Two hydrophobic low‐molecular‐mass protein fractions of pulmonary surfactant

  European Journal of Biochemistry · 1987 · https://doi.org/10.1111/j.1432-1033.1987.tb13414.x

Current projects

No projects listed.