Georg Schett

Research interests

Publications

• CD19 CAR T-Cell Therapy in Autoimmune Disease — A Case Series with Follow-up

  New England Journal of Medicine · 2024 · https://doi.org/10.1056/nejmoa2308917

• Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-02017-5

• CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus

  New England Journal of Medicine · 2021 · 10.1056/nejmc2107725

• EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update

  Annals of the Rheumatic Diseases · 2020 · https://doi.org/10.1136/annrheumdis-2020-217159

• EULAR definition of difficult-to-treat rheumatoid arthritis

  Annals of the Rheumatic Diseases · 2020 · 10.1136/annrheumdis-2020-217344

• Locally renewing resident synovial macrophages provide a protective barrier for the joint

  Nature · 2019 · 10.1038/s41586-019-1471-1

• Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis

  Nature Reviews Rheumatology · 2018 · 10.1038/s41584-018-0109-2

• Enthesitis: from pathophysiology to treatment

  Nature Reviews Rheumatology · 2017 · 10.1038/nrrheum.2017.188

• Trial of Tocilizumab in Giant-Cell Arteritis

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1613849

• Pathogenetic insights from the treatment of rheumatoid arthritis

  The Lancet · 2017 · https://doi.org/10.1016/s0140-6736(17)31472-1

• Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

  Nature Communications · 2017 · 10.1038/s41467-017-02490-4

• Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

  Cell Death and Differentiation · 2016 · 10.1038/cdd.2016.11

• European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update

  Annals of the Rheumatic Diseases · 2016 · 10.1136/annrheumdis-2015-208337

• EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice

  Annals of the Rheumatic Diseases · 2015 · 10.1136/annrheumdis-2014-206971

• Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

  Nature Medicine · 2014 · 10.1038/nm.3547

• Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

  Nature Communications · 2012 · 10.1038/ncomms1734

• Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

  Nature Reviews Rheumatology · 2012 · 10.1038/nrrheum.2012.153

• Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

  Journal of Clinical Investigation · 2012 · 10.1172/jci60975

• The Pathogenesis of Rheumatoid Arthritis

  New England Journal of Medicine · 2011 · https://doi.org/10.1056/nejmra1004965

• Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

  Nature · 2010 · 10.1038/nature09387

• Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE

  The Journal of Experimental Medicine · 2008 · 10.1084/jem.20081165

• Cytokines in the pathogenesis of rheumatoid arthritis

  Nature reviews. Immunology · 2007 · https://doi.org/10.1038/nri2094

• Dickkopf-1 is a master regulator of joint remodeling

  Nature Medicine · 2007 · 10.1038/nm1538

• Osteoprotegerin Is a Risk Factor for Progressive Atherosclerosis and Cardiovascular Disease

  Circulation · 2004 · 10.1161/01.cir.0000127957.43874.bb

• Osteoclasts are essential for TNF-α–mediated joint destruction

  Journal of Clinical Investigation · 2002 · 10.1172/jci15582

Current projects

No projects listed.